YEATS4 and CEP162

Data Source:
BioGRID (two hybrid)

		YEATS4	CEP162
Description		YEATS domain containing 4	centrosomal protein 162
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Matrix Nuclear Membrane NuA4 Histone Acetyltransferase Complex	Nucleus Centrosome Centriole Spindle Cytosol Axonemal Microtubule
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Protein C-terminus Binding Lysine-acetylated Histone Binding Modification-dependent Protein Binding	Protein Binding
	Biological Process	Mitotic Cell Cycle Cytoskeleton Organization Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Cilium Assembly Ciliary Basal Body-plasma Membrane Docking
Pathways		HATs acetylate histones Activation of the TFAP2 (AP-2) family of transcription factors	Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Complete remission in asthma ( 29786918) Depressive symptoms x independent stressful life events interaction (1df test) ( 30718454) Height ( 31562340 18391951) Metabolite levels ( 23823483) Response to antidepressants (symptom remission) ( 29160301) Response to diuretic therapy ( 18591461) Response to SSRI in MDD or conscientiouness ( 29559929) Thyroid stimulating hormone levels ( 32769997)	Diabetic retinopathy in type 2 diabetes ( 25364816)
Interacting Genes		17 interacting genes: ANKK1 CEP162 FRMD4A GTF2F2 H3C1 MLLT10 MRGBP MYCN NUMA1 PFDN1 RNF8 SMARCB1 TACC1 TACC2 TFAP2B TPM1 TRIM54	7 interacting genes: CPNE4 KDM1A MTDH PRMT1 PRMT8 SPP1 YEATS4
Entrez ID		8089	22832
HPRD ID		03666	10796
Ensembl ID		ENSG00000127337	ENSG00000135315
Uniprot IDs		F8W0J4 O95619	Q5TB80
PDB IDs		5VNA 5VNB 5XTZ 5Y8V
Enriched GO Terms of Interacting Partners?
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