TACC2 and AURKC

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TACC2	AURKC
Description		transforming acidic coiled-coil containing protein 2	aurora kinase C
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Microtubule Organizing Center Cytosol Plasma Membrane	Condensed Chromosome Nucleus Cytoplasm Spindle Spindle Microtubule Midbody Spindle Pole Centrosome Chromosome Passenger Complex Spindle Midzone
	Molecular Function	Nuclear Hormone Receptor Binding	Protein Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Binding ATP Binding Histone Serine Kinase Activity Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Cell Population Proliferation Cerebral Cortex Development	Protein Phosphorylation Mitotic Spindle Organization Spermatogenesis Attachment Of Spindle Microtubules To Kinetochore Histone Modification Regulation Of Cytokinesis Positive Regulation Of Cytokinesis Histone-serine Phosphorylation Oocyte Development Mitotic Spindle Midzone Assembly Cell Division Meiotic Cell Cycle
Pathways
Drugs			SNS-314 Fostamatinib
Diseases
GWAS		Hepcidin/ferritin ratio ( 27846281) Metabolite risk score for predicting weight gain ( 31560688) Myopia (pathological) ( 23049088) Normal facial asymmetry (angle of surface orientation score) ( 30631343) Obesity-related traits ( 23251661) Opioid dependence ( 31250797) Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Total body bone mineral density ( 29304378)
Interacting Genes		15 interacting genes: AURKC BORCS6 CLK2 CLVS2 CREBBP EP300 GRAMD4 HMG20B KAT2A KAT2B PPP1CC RXRB SMARCB1 TGM1 YEATS4	13 interacting genes: BIRC5 BIRC7 BRCA1 CADPS CENPA H3C1 INCENP LNX1 NEDD4 NEDD4L OTX2 SRPK1 TACC2
Entrez ID		10579	6795
HPRD ID		05600	04605
Ensembl ID		ENSG00000138162	ENSG00000105146
Uniprot IDs		B2RWP4 B7ZMJ9 D6RAA5 O95359 Q4VXL4 Q4VXL8	Q9UQB9
PDB IDs			6GR8 6GR9
Enriched GO Terms of Interacting Partners?
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