YEATS4 and ANKK1

Data Source:
BioGRID (two hybrid)

		YEATS4	ANKK1
Description		YEATS domain containing 4	ankyrin repeat and kinase domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Matrix Nuclear Membrane NuA4 Histone Acetyltransferase Complex	Nucleus Cytoplasm Cell Projection
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Protein C-terminus Binding Lysine-acetylated Histone Binding Modification-dependent Protein Binding	Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Mitotic Cell Cycle Cytoskeleton Organization Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Protein Phosphorylation Regulation Of Cell Cycle Process
Pathways		HATs acetylate histones Activation of the TFAP2 (AP-2) family of transcription factors
Drugs			Fostamatinib
Diseases
GWAS		Complete remission in asthma ( 29786918) Depressive symptoms x independent stressful life events interaction (1df test) ( 30718454) Height ( 31562340 18391951) Metabolite levels ( 23823483) Response to antidepressants (symptom remission) ( 29160301) Response to diuretic therapy ( 18591461) Response to SSRI in MDD or conscientiouness ( 29559929) Thyroid stimulating hormone levels ( 32769997)	Alcohol consumption (drinks per week) ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Body mass index ( 26426971) Experiencing mood swings ( 29500382)
Interacting Genes		17 interacting genes: ANKK1 CEP162 FRMD4A GTF2F2 H3C1 MLLT10 MRGBP MYCN NUMA1 PFDN1 RNF8 SMARCB1 TACC1 TACC2 TFAP2B TPM1 TRIM54	6 interacting genes: C12orf57 C2CD6 CHN1 CHN2 HIF1AN YEATS4
Entrez ID		8089	255239
HPRD ID		03666	10580
Ensembl ID		ENSG00000127337	ENSG00000170209
Uniprot IDs		F8W0J4 O95619	Q8NFD2
PDB IDs		5VNA 5VNB 5XTZ 5Y8V
Enriched GO Terms of Interacting Partners?
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