PGRMC2 and PEX16

Data Source:
BioGRID (two hybrid)

		PGRMC2	PEX16
Description		progesterone receptor membrane component 2	peroxisomal biogenesis factor 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endomembrane System Membrane Integral Component Of Membrane	Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Steroid Hormone Receptor Activity Steroid Binding Protein Binding Heme Transmembrane Transporter Activity Heme Binding	Protein Binding Protein C-terminus Binding
	Biological Process	Heme Transport Steroid Hormone Mediated Signaling Pathway Adipose Tissue Development	Protein Targeting To Peroxisome Peroxisome Organization Peroxisome Membrane Biogenesis Protein Import Into Peroxisome Matrix Protein To Membrane Docking ER-dependent Peroxisome Organization Protein Import Into Peroxisome Membrane ER-dependent Peroxisome Localization
Pathways			Class I peroxisomal membrane protein import Class I peroxisomal membrane protein import
Drugs
Diseases			Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		Bone mineral density (total hip) ( 29883787)	Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Axial length ( 24144296)
Interacting Genes		57 interacting genes: AQP10 ART5 BAG4 C5 COX20 CYB561D2 CYP4F2 DGAT2L6 DHRSX EI24 FA2H FAXDC2 FXYD6 FXYD6-FXYD2 GET3 GHITM GPR151 ITGAM ITPRIP LPAR3 MALL MFHAS1 MFSD5 ORMDL1 PEDS1-UBE2V1 PEX16 PGRMC1 PLLP PMP22 RNF8 RUSF1 SFXN1 SLC16A13 SLC30A8 SLC38A1 SLC39A13 SLC9B2 SMPD2 ST6GAL2 STX3 TAS2R19 TECR TF TMEM107 TMEM187 TMEM19 TMEM208 TMEM60 TMEM86A TMEM86B TSPAN2 UBXN8 VAPA VEZT YIPF2 ZDHHC21 ZFPL1	26 interacting genes: AQP6 BDKRB2 CLEC10A CREB3L1 DEXI EBAG9 ERGIC3 FCER1G FFAR2 GPR152 KCNJ6 LEPROTL1 MFSD14B MMGT1 PDZK1IP1 PEX19 PEX3 PGRMC2 REEP4 SLC10A1 SLC10A6 SLC18A1 SLC35C2 TMX2 TNFRSF17 ZDHHC15
Entrez ID		10424	9409
HPRD ID		09665	04526
Ensembl ID		ENSG00000164040	ENSG00000121680
Uniprot IDs		O15173	Q9Y5Y5
PDB IDs
Enriched GO Terms of Interacting Partners?
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