PGRMC2 and SLC39A13

Data Source:
BioGRID (two hybrid)

		PGRMC2	SLC39A13
Description		progesterone receptor membrane component 2	solute carrier family 39 member 13
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endomembrane System Membrane Integral Component Of Membrane	Endoplasmic Reticulum Golgi Apparatus Integral Component Of Membrane Integral Component Of Golgi Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Steroid Hormone Receptor Activity Steroid Binding Protein Binding Heme Transmembrane Transporter Activity Heme Binding	Zinc Ion Transmembrane Transporter Activity Protein Binding Protein Homodimerization Activity
	Biological Process	Heme Transport Steroid Hormone Mediated Signaling Pathway Adipose Tissue Development	Cellular Zinc Ion Homeostasis Response To Zinc Ion Connective Tissue Development Zinc Ion Transmembrane Transport
Pathways
Drugs
Diseases			Ehlers-Danlos syndrome (EDS), including: EDS classical type (EDS1/2); EDS hypermobility type (EDS3); EDS vascular type (EDS4); EDS kyphoscoliosis type (EDS6); EDS arthrochalasia type (EDS7A/7B); EDS dermatospraxis type (EDS7C); EDS autosomal recessive cardiac valvular form (EDSCV); EDS musculocontractural type (EDSMC); EDS progeroid form (EDSP); Tenascin-X deficiency (TNXD); Brittle cornea syndrome (EDS6B); EDS-like spondylocheiro dysplasia (SCD-EDS)
GWAS		Bone mineral density (total hip) ( 29883787)	Alcohol use disorder (total score) ( 30336701) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Blood urea nitrogen levels ( 31152163) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic kidney disease ( 31152163) Diastolic blood pressure ( 28739976 27618452) Estimated glomerular filtration rate ( 31152163 31015462) Fruit consumption ( 32066663) Global electrical heterogeneity phenotypes ( 29622589) Hip circumference ( 25673412) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Neuroticism ( 29255261) Problematic alcohol use ( 32451486) Refractive error ( 32231278) Systolic blood pressure ( 28739976 27618452 30578418) Waist circumference ( 25673412)
Interacting Genes		57 interacting genes: AQP10 ART5 BAG4 C5 COX20 CYB561D2 CYP4F2 DGAT2L6 DHRSX EI24 FA2H FAXDC2 FXYD6 FXYD6-FXYD2 GET3 GHITM GPR151 ITGAM ITPRIP LPAR3 MALL MFHAS1 MFSD5 ORMDL1 PEDS1-UBE2V1 PEX16 PGRMC1 PLLP PMP22 RNF8 RUSF1 SFXN1 SLC16A13 SLC30A8 SLC38A1 SLC39A13 SLC9B2 SMPD2 ST6GAL2 STX3 TAS2R19 TECR TF TMEM107 TMEM187 TMEM19 TMEM208 TMEM60 TMEM86A TMEM86B TSPAN2 UBXN8 VAPA VEZT YIPF2 ZDHHC21 ZFPL1	9 interacting genes: CD40 CREB3 F2RL1 MAPK8IP2 OPRM1 PGRMC2 REL SLC16A2 TCF4
Entrez ID		10424	91252
HPRD ID		09665	12287
Ensembl ID		ENSG00000164040	ENSG00000165915
Uniprot IDs		O15173	Q96H72
PDB IDs
Enriched GO Terms of Interacting Partners?
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