PGRMC2 and SLC9B2

Data Source:
BioGRID (two hybrid)

		PGRMC2	SLC9B2
Description		progesterone receptor membrane component 2	solute carrier family 9 member B2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endomembrane System Membrane Integral Component Of Membrane	Mitochondrial Inner Membrane Plasma Membrane Endosome Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Synaptic Vesicle Membrane Mitochondrial Membrane Sperm Principal Piece
	Molecular Function	Steroid Hormone Receptor Activity Steroid Binding Protein Binding Heme Transmembrane Transporter Activity Heme Binding	Monovalent Cation:proton Antiporter Activity Protein Binding Lithium:proton Antiporter Activity Sodium:proton Antiporter Activity Identical Protein Binding
	Biological Process	Heme Transport Steroid Hormone Mediated Signaling Pathway Adipose Tissue Development	Sodium Ion Transport Flagellated Sperm Motility Ion Transmembrane Transport Sodium Ion Transmembrane Transport Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Clathrin-dependent Endocytosis Proton Transmembrane Transport Positive Regulation Of Osteoclast Development
Pathways			Stimuli-sensing channels
Drugs
Diseases
GWAS		Bone mineral density (total hip) ( 29883787)	Estimated glomerular filtration rate ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Type 2 diabetes ( 30054458)
Interacting Genes		57 interacting genes: AQP10 ART5 BAG4 C5 COX20 CYB561D2 CYP4F2 DGAT2L6 DHRSX EI24 FA2H FAXDC2 FXYD6 FXYD6-FXYD2 GET3 GHITM GPR151 ITGAM ITPRIP LPAR3 MALL MFHAS1 MFSD5 ORMDL1 PEDS1-UBE2V1 PEX16 PGRMC1 PLLP PMP22 RNF8 RUSF1 SFXN1 SLC16A13 SLC30A8 SLC38A1 SLC39A13 SLC9B2 SMPD2 ST6GAL2 STX3 TAS2R19 TECR TF TMEM107 TMEM187 TMEM19 TMEM208 TMEM60 TMEM86A TMEM86B TSPAN2 UBXN8 VAPA VEZT YIPF2 ZDHHC21 ZFPL1	1 interacting genes: PGRMC2
Entrez ID		10424	133308
HPRD ID		09665	14051
Ensembl ID		ENSG00000164040	ENSG00000164038
Uniprot IDs		O15173	A0A024RDJ7 B7Z488 B7Z676 E9PE63 Q86UD5
PDB IDs
Enriched GO Terms of Interacting Partners?
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