SAP18 and SUFU

  • Data Source:
  • HPRD (two hybrid, in vivo, in vitro)

SAP18

SUFU

Description Sin3A associated protein 18 SUFU negative regulator of hedgehog signaling
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359)
  • Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359)
  • Allergy ( 27182965)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Body mass index ( 25673413 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index in physically active individuals ( 28448500)
  • Brain morphology (MOSTest) ( 32665545)
  • Creatinine levels ( 29403010)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Eosinophil counts ( 32888494)
  • Estimated glomerular filtration rate ( 30604766)
  • Glomerular filtration rate ( 29403010)
  • Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)
  • Height ( 28552196)
  • Nickel levels ( 26025379)
  • Optic disc size ( 31809533)
  • Platelet count ( 32888494)
  • Prostate cancer ( 23535732)
  • Refractive error ( 32231278)
  • Sum eosinophil basophil counts ( 27863252)
  • Systolic blood pressure ( 30578418)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for body mass index ( 25673412)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • White blood cell count ( 29403010)
Interacting Genes 15 interacting genes: DEF6 ERBB3 HDAC1 IKZF1 INCA1 NOL12 NTAQ1 POLE2 RBM39 RNPS1 RPS3A SIN3A SUFU TADA3 TSC22D2 50 interacting genes: ABI3 BFSP2 BTRC CRTC2 CRX DISC1 FBXL17 FXR1 GLI1 GLI2 GLI3 GLIS3 HDX HMGA1 HNRNPA1 ITCH KRT27 KRT75 L3MBTL3 LAMTOR3 LCA5 LGALS3 LZTS1 MAGEL2 MEOX2 MID1IP1 NCOA3 PEX26 PIAS1 QPRT RBPJ RCN3 RNF19A SAP18 SETDB1 SH3RF1 SLC41A3 STK36 STX19 TLE5 UBE2D1 ZIC1 ZNF114 ZNF219 ZNF263 ZNF330 ZNF446 ZNF763 ZNF764 ZSCAN18
Entrez ID 10284 51684
HPRD ID 04256 06124
Ensembl ID ENSG00000150459 ENSG00000107882
Uniprot IDs O00422 A0A223LX15 Q9UMX1
PDB IDs 2HDE 1M1L 4BL8 4BL9 4BLA 4BLB 4BLD 4KM8 4KM9 4KMD 4KMH
Enriched GO Terms of Interacting Partners?
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