SUFU and HDX

  • Data Source:
  • BioGRID (two hybrid, two hybrid)

SUFU

HDX

Description SUFU negative regulator of hedgehog signaling highly divergent homeobox
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359)
  • Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359)
  • Allergy ( 27182965)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Body mass index ( 25673413 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index in physically active individuals ( 28448500)
  • Brain morphology (MOSTest) ( 32665545)
  • Creatinine levels ( 29403010)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Eosinophil counts ( 32888494)
  • Estimated glomerular filtration rate ( 30604766)
  • Glomerular filtration rate ( 29403010)
  • Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)
  • Height ( 28552196)
  • Nickel levels ( 26025379)
  • Optic disc size ( 31809533)
  • Platelet count ( 32888494)
  • Prostate cancer ( 23535732)
  • Refractive error ( 32231278)
  • Sum eosinophil basophil counts ( 27863252)
  • Systolic blood pressure ( 30578418)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for body mass index ( 25673412)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • White blood cell count ( 29403010)
  • Dentures ( 31235808)
  • Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)
Interacting Genes 50 interacting genes: ABI3 BFSP2 BTRC CRTC2 CRX DISC1 FBXL17 FXR1 GLI1 GLI2 GLI3 GLIS3 HDX HMGA1 HNRNPA1 ITCH KRT27 KRT75 L3MBTL3 LAMTOR3 LCA5 LGALS3 LZTS1 MAGEL2 MEOX2 MID1IP1 NCOA3 PEX26 PIAS1 QPRT RBPJ RCN3 RNF19A SAP18 SETDB1 SH3RF1 SLC41A3 STK36 STX19 TLE5 UBE2D1 ZIC1 ZNF114 ZNF219 ZNF263 ZNF330 ZNF446 ZNF763 ZNF764 ZSCAN18 16 interacting genes: BOLA1 BOLA2 BOLA2B CCDC57 CTNNA3 FHL5 GCC1 LMO1 LNX1 MID2 POLR1C RTN4IP1 SUFU TSGA10 TTC5 ZBTB16
Entrez ID 51684 139324
HPRD ID 06124 06550
Ensembl ID ENSG00000107882 ENSG00000165259
Uniprot IDs A0A223LX15 Q9UMX1 Q7Z353
PDB IDs 1M1L 4BL8 4BL9 4BLA 4BLB 4BLD 4KM8 4KM9 4KMD 4KMH 2DA4
Enriched GO Terms of Interacting Partners?
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