SAP18 and NOL12

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SAP18	NOL12
Description		Sin3A associated protein 18	nucleolar protein 12
Image			No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleus Nucleoplasm Cytosol Nuclear Body Nuclear Speck Exon-exon Junction Complex ASAP Complex	Nucleolus
	Molecular Function	Transcription Corepressor Activity RNA Binding Protein Binding Transcription Factor Binding	RNA Binding Protein Binding RRNA Binding Identical Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II MRNA Processing RNA Splicing Positive Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways		HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS	Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Basophil count ( 32888494) Brain morphology (MOSTest) ( 32665545) Pulse pressure ( 30224653)
Interacting Genes		15 interacting genes: DEF6 ERBB3 HDAC1 IKZF1 INCA1 NOL12 NTAQ1 POLE2 RBM39 RNPS1 RPS3A SIN3A SUFU TADA3 TSC22D2	19 interacting genes: APP BEND7 CDCA7L CDK4 CEP70 DVL2 DVL3 KIAA1191 KRTAP10-6 KRTAP10-7 MCC SAP18 SF3B3 SLC25A38 SOD2 SPANXN2 SSX2IP TERF1 TSPYL2
Entrez ID		10284	79159
HPRD ID		04256	17537
Ensembl ID		ENSG00000150459	ENSG00000273899
Uniprot IDs		O00422	A0A024R1M6 Q9UGY1
PDB IDs		2HDE
Enriched GO Terms of Interacting Partners?
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