STAC3 and NSD3

Data Source:
BioGRID (two hybrid)

		STAC3	NSD3
Description		SH3 and cysteine rich domain 3	nuclear receptor binding SET domain protein 3
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Voltage-gated Calcium Channel Complex T-tubule Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Synapse	Chromatin Nucleus Nucleoplasm
	Molecular Function	Protein Binding Identical Protein Binding Metal Ion Binding	Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding Histone Methyltransferase Activity (H3-K36 Specific) Transcription Regulator Activator Activity
	Biological Process	Skeletal Muscle Contraction Neuromuscular Synaptic Transmission Intracellular Signal Transduction Skeletal Muscle Fiber Development Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Localization To Plasma Membrane	Regulation Of Transcription, DNA-templated Histone H3-K36 Methylation Histone Methylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Histone H3-K36 Trimethylation
Pathways			PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 25056061 29483656)
Interacting Genes		38 interacting genes: ANKRD36 BAZ2B C1orf35 CSNK2A1 DIP2A EAF1 EAF2 ENKD1 FAM124A FAM133A FAM90A1 FAM9A FGF11 FGF12 GAS8 GIGYF1 GRB7 HMGXB4 INO80B JMJD6 L3MBTL2 MAB21L3 MFAP1 NKAPD1 NSD3 PPARA RPL22 RPL9 RPS25 SPANXN2 SPANXN3 SREK1IP1 TCEA2 TNFAIP8L1 U2AF2 VCX2 ZCCHC10 ZGPAT	42 interacting genes: AKT1 ATM BCAR3 CASP8 CBLC CBX3 CBX5 CDKN2A CHEK2 DAXX DOCK7 ESR1 ETV3 FGFR4 GLIS2 GLYR1 H1-1 H3-5 H3C1 H4C1 HOXC4 MLLT6 MNDA MYC NFIC PAX2 PPM1D RB1CC1 SEPTIN6 SLU7 SOX3 SOX4 SPAG8 STAC3 TCF3 TEAD2 TERT TGFB1 TRIM55 TRIM63 UBE2I ZNF557
Entrez ID		246329	54904
HPRD ID		11606	06155
Ensembl ID		ENSG00000185482	ENSG00000147548
Uniprot IDs		A0A024RB38 Q96MF2	Q9BZ95
PDB IDs		2DB6 6B29 6UY7 6UY8 6UY9	2DAQ 2NCZ 2ND1 4GND 4GNE 4GNF 4GNG 4RXJ 5UPD 6CEN 6G24 6G25 6G27 6G29 6G2B 6G2C 6G2E 6G2F 6G2O 6G3P 6G3T 7CRP 7CRQ 7CRR
Enriched GO Terms of Interacting Partners?
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