STAC3 and GAS8

Data Source:
BioGRID (two hybrid)

		STAC3	GAS8
Description		SH3 and cysteine rich domain 3	growth arrest specific 8
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Voltage-gated Calcium Channel Complex T-tubule Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Synapse	Golgi Apparatus Cytosol Microtubule Plasma Membrane Cilium Axoneme Motile Cilium Ciliary Basal Body
	Molecular Function	Protein Binding Identical Protein Binding Metal Ion Binding	Molecular_function Protein Binding Microtubule Binding
	Biological Process	Skeletal Muscle Contraction Neuromuscular Synaptic Transmission Intracellular Signal Transduction Skeletal Muscle Fiber Development Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Localization To Plasma Membrane	Negative Regulation Of Cell Population Proliferation Flagellated Sperm Motility Cellular Protein Localization Axoneme Assembly Positive Regulation Of Smoothened Signaling Pathway Cilium Movement Involved In Cell Motility Positive Regulation Of Protein Localization To Cilium Regulation Of Microtubule Binding
Pathways			Activation of SMO
Drugs
Diseases
GWAS		Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 25056061 29483656)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		38 interacting genes: ANKRD36 BAZ2B C1orf35 CSNK2A1 DIP2A EAF1 EAF2 ENKD1 FAM124A FAM133A FAM90A1 FAM9A FGF11 FGF12 GAS8 GIGYF1 GRB7 HMGXB4 INO80B JMJD6 L3MBTL2 MAB21L3 MFAP1 NKAPD1 NSD3 PPARA RPL22 RPL9 RPS25 SPANXN2 SPANXN3 SREK1IP1 TCEA2 TNFAIP8L1 U2AF2 VCX2 ZCCHC10 ZGPAT	111 interacting genes: ARL6IP1 BCAR3 BHLHB9 BORCS6 BYSL C1orf35 CARD10 CARD9 CBFA2T3 CCDC125 CCDC146 CCDC6 CCHCR1 CCNG1 CDC37 CDR2 CEP70 CFAP53 CINP CKS1B COG6 CPSF7 CRYBB1 CT45A1 CWF19L2 CYSRT1 DAXX DDX17 DISC1 DMAP1 EAF1 EHHADH EIF1AD ERCC1 EVI5L FAM161A FAM161B FHL2 GADD45GIP1 GCC1 GEM GOLGA2 GRIPAP1 GSTA4 HEXIM2 HOMER3 HOMEZ HOXA1 HSF2BP IGFBP6 KDM1A KRT14 KRT15 KRT16 KRT27 L3MBTL2 L3MBTL3 LASP1 LHX3 LMO1 LMO2 LZTS1 MAD1L1 MFAP1 MID2 MRFAP1L1 NDOR1 NKAPD1 PLK4 PNKP PNMA5 POLR1C POTEB3 PPFIA1 PRDM14 PRMT5 PRPF18 RALBP1 RBAK RINT1 RUBCN SCNM1 SKIL SORBS3 SP7 SPATA18 SPG21 STAC3 TCEA2 THAP1 TNFAIP3 TRAF2 TRAF5 TRIM41 TRIM54 TSFM TSGA10IP TXLNA TXLNB USHBP1 YES1 YJU2 ZBTB22 ZBTB26 ZBTB39 ZNF212 ZNF250 ZNF572 ZNF620 ZNF629 ZNF792
Entrez ID		246329	2622
HPRD ID		11606	05533
Ensembl ID		ENSG00000185482	ENSG00000141013
Uniprot IDs		A0A024RB38 Q96MF2	A0A087WZT7 A0A384MR00 B7Z1U9 O95995
PDB IDs		2DB6 6B29 6UY7 6UY8 6UY9
Enriched GO Terms of Interacting Partners?
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