SENP1

Description		SUMO specific peptidase 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Focal Adhesion Nuclear Membrane
	Molecular Function	Endopeptidase Activity Protein Binding SUMO-specific Protease Activity SUMO-specific Isopeptidase Activity
	Biological Process	Proteolysis Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Protein Sumoylation Protein Desumoylation Positive Regulation Of Transcription By RNA Polymerase II Apoptotic Signaling Pathway
Pathways		SUMO is proteolytically processed
Drugs
Diseases
GWAS		Glycated hemoglobin levels ( 28898252) Hematocrit ( 32888494) Hemoglobin ( 32888494) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Macular thickness ( 30535121) Reticulocyte count ( 32888494) Rheumatoid arthritis ( 30891314)
Novel Interacting Genes		2 novel interacting genes: KEAP1 PRIM1
Interacting Genes		22 interacting genes: APP CAV3 GCM1 HDAC1 HIPK2 KCNK1 NACC1 PARP1 PIAS3 PIM1 PML RABGAP1 RANBP2 RANGAP1 RPL11 SP100 SUMO1 SUMO2 SUMO3 UBE2K USP25 USP28
Entrez ID		29843
HPRD ID		07153
Ensembl ID		ENSG00000079387
Uniprot IDs		Q6N001 Q7Z3G1 Q9P0U3
PDB IDs		2CKG 2CKH 2G4D 2IY0 2IY1 2IYC 2IYD 2XPH 2XRE 6NNQ
Enriched GO Terms of Interacting Partners?
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