SETDB1 and POLA2

  • Number of citations of the paper that reports this interaction (PubMedID 16169070)
  • 888

SETDB1

POLA2

Description SET domain bifurcated histone lysine methyltransferase 1 DNA polymerase alpha 2, accessory subunit
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Body mass index ( 26426971)
  • Caffeine consumption from coffee or tea ( 33287642)
  • Caffeine consumption from tea ( 33287642)
  • Chronic kidney disease ( 20383146)
  • Coffee consumption ( 31046077)
  • Cutaneous squamous cell carcinoma ( 32041948)
  • Hip circumference adjusted for BMI ( 34021172)
  • Melanoma ( 21983785)
  • Neurological blood protein biomarker levels ( 31320639)
  • Nevus count or cutaneous melanoma ( 30429480)
Interacting Genes 110 interacting genes: AIFM1 AKT1 ANXA7 APC APLP1 ASAH1 ATF7IP ATF7IP2 BAG6 BARD1 BHLHE40 BID BRIX1 BTBD2 C11orf1 CBX8 CCDC106 CDK4 CDKN1A CLSTN1 CREBBP CRELD1 DAP DLEU1 DNMT3A ECSIT ERG ERH FAM118B FLYWCH1 GIPC2 GPS2 GRB7 GSTO1 H3-4 H3C1 H3C15 H4-16 HDAC1 HDAC2 HMOX2 HSF2BP HSPB3 JARID2 KDM1A LRIF1 LUC7L2 MAD2L1BP MAP4K5 MBD1 MDM2 MOB4 MRPL44 MZT2B NIPSNAP3A OLFML3 ORAI2 PABPC4 PAFAH1B3 PCDHA4 PCYT2 PGAM5 PHF10 PIAS4 PLEKHA4 POLA2 PPA1 PPP1R8 PRKRA PSMD11 PSME1 PTPRS QTRT1 RIF1 RNF10 S100A10 SAT1 SERPINB9 SIN3A SIN3B SKIL SLC38A3 SMN1 SNIP1 SUFU SULT1E1 SUMO2 TARDBP TCERG1 THAP8 TK1 TOB1 TOLLIP TPI1 TRBV2 TRDMT1 TRIB3 TRIM16 TRIM28 TRIP6 TSC22D1 TSPAN15 TTR TXNDC9 UBE2I ULK2 USP11 VIM ZFP64 ZNF24 41 interacting genes: AGO2 AKTIP APP ARL2 ASCC2 ATL3 ATP5F1C CATSPERZ CPE CRELD1 DCP2 DDX24 DHX34 EIF6 EZH2 FAM219A FGFR3 FRZB HDAC6 HELB HGH1 IGFBP3 KCNE3 KDM2A KLF6 LRPAP1 MFHAS1 NR4A1 PARP1 POLA1 PRIM2 PRPF38A RBM23 SAC3D1 SETDB1 SNU13 STK40 TMEM216 ULK2 XPNPEP1 ZNRD2
Entrez ID 9869 23649
HPRD ID 06828 10160
Ensembl ID ENSG00000143379 ENSG00000014138
Uniprot IDs Q15047 Q14181
PDB IDs 3DLM 4X3S 5KCH 5KCO 5KE2 5KE3 5KH6 5QT1 5QT2 6AU2 6AU3 6BHD 6BHE 6BHG 6BHH 6BHI 6BPI 2KEB 4E2I 4Y97 5EXR
Enriched GO Terms of Interacting Partners?
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