QPRT and GIT2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		QPRT	GIT2
Description		quinolinate phosphoribosyltransferase	GIT ArfGAP 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome Catalytic Complex	Nucleoplasm Focal Adhesion
	Molecular Function	Nicotinate-nucleotide Diphosphorylase (carboxylating) Activity Protein Binding Identical Protein Binding	GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	NAD Biosynthetic Process NAD Metabolic Process Quinolinate Catabolic Process	Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Catalytic Activity
Pathways		Nicotinate metabolism	CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RHOU GTPase cycle RAC3 GTPase cycle RHOV GTPase cycle
Drugs		Niacin
Diseases
GWAS			Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolic syndrome ( 20694148) Metabolite levels ( 23823483) Metabolite levels (MHPG) ( 23319000)
Interacting Genes		11 interacting genes: ADAMTSL4 BCKDK ETS1 GIT2 KRT40 KRTAP1-1 KRTAP10-3 KRTAP10-8 KRTAP4-12 NOTCH2NLA SUFU	48 interacting genes: ACTG1 ACTN1 ARHGEF6 ARHGEF7 ATF5 C4BPA CALCOCO2 CDC42 CORO1A E2F2 EDC4 GCH1 GET4 GIT1 GRK2 GUSB HGD HNRNPUL1 IKBKG KCTD5 KRT18 LAMTOR5 LMNB1 MVP NFKBIB NME2 PAK1 PAK3 PCLO POLR1B PROX1 PXN QPRT RCVRN RUFY1 RUSC2 SAFB2 SH3GLB2 SMAD3 SPOP TGFB1I1 TNFAIP3 TNIP1 TRAF1 TSN UBQLN1 USHBP1 YWHAG
Entrez ID		23475	9815
HPRD ID		06950	09779
Ensembl ID		ENSG00000103485	ENSG00000139436
Uniprot IDs		B4DDH4 Q15274 V9HWJ5	F8VXI9 F8W822 Q14161 Q68DM7 Q6FI58
PDB IDs		2JBM 4KWV 4KWW 5AYX 5AYY 5AYZ
Enriched GO Terms of Interacting Partners?
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