ARHGEF6 and GIT2

  • Number of citations of the paper that reports this interaction (PubMedID 28514442)
  • 406
  • Data Source:
  • BioGRID (affinity chromatography technology, two hybrid, affinity chromatography technology)

ARHGEF6

GIT2

Description Rac/Cdc42 guanine nucleotide exchange factor 6 GIT ArfGAP 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bipolar disorder ( 31043756)
  • Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980)
  • Metabolic syndrome ( 20694148)
  • Metabolite levels ( 23823483)
  • Metabolite levels (MHPG) ( 23319000)
Interacting Genes 38 interacting genes: ADAM15 ARAP3 ARHGEF7 BMPR1B CAPNS1 CBFA2T3 CCDC33 CDC42 CDK6 EPHB2 GIT1 GIT2 GOLGA2 GPRASP2 HSF2BP KRT27 NUTM1 PAK1 PAK2 PAK3 PARVB PNMA1 POU6F2 RWDD2A SH2D1A SH3GL3 SIRPA SMAD1 SMAD2 SMAD3 TGFBR1 TGFBR2 TMEM108 TP53BP2 TRAF2 TRIM54 YWHAG ZNF580 48 interacting genes: ACTG1 ACTN1 ARHGEF6 ARHGEF7 ATF5 C4BPA CALCOCO2 CDC42 CORO1A E2F2 EDC4 GCH1 GET4 GIT1 GRK2 GUSB HGD HNRNPUL1 IKBKG KCTD5 KRT18 LAMTOR5 LMNB1 MVP NFKBIB NME2 PAK1 PAK3 PCLO POLR1B PROX1 PXN QPRT RCVRN RUFY1 RUSC2 SAFB2 SH3GLB2 SMAD3 SPOP TGFB1I1 TNFAIP3 TNIP1 TRAF1 TSN UBQLN1 USHBP1 YWHAG
Entrez ID 9459 9815
HPRD ID 02226 09779
Ensembl ID ENSG00000129675 ENSG00000139436
Uniprot IDs B7Z3C7 Q15052 Q8N4Q3 F8VXI9 F8W822 Q14161 Q68DM7 Q6FI58
PDB IDs 1UJY 1WYR
Enriched GO Terms of Interacting Partners?
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