FXYD6 and TMEM154

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FXYD6	TMEM154
Description		FXYD domain containing ion transport regulator 6	transmembrane protein 154
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Glutamatergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane	Integral Component Of Membrane
	Molecular Function	Molecular_function Protein Binding Sodium Channel Regulator Activity	Protein Binding
	Biological Process	Ion Transport Biological_process Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways		Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs
Diseases
GWAS		Hippocampal volume in Alzheimer's disease dementia ( 29274321) Myopia ( 27182965)	Gut microbiota relative abundance (unclassified genus belonging to family Lachnospiraceae) ( 33208821) Hip circumference ( 28552196) Obstructive sleep apnea during REM sleep (apnea hypopnea index) ( 29077507) Type 2 diabetes ( 24509480 30054458 29358691 30297969 32499647 30718926 28869590)
Interacting Genes		65 interacting genes: APCDD1L APH1A AQP6 ARL13B BCAR1 C4BPA CCDC90B CD74 CERS4 CLDN7 CLEC10A CREB3 CREB3L1 DERL2 EBP ELOVL2 ELOVL4 ERGIC3 FCER1G FFAR2 FPR2 GDF9 GJA8 GPR42 HAUS2 JAGN1 KCNJ6 LHFPL2 LHFPL5 LMNA MFF MGST3 MMGT1 OCIAD1 PEX12 PGRMC2 PPP1CC RBM48 RHBDL1 RHCG RNASEK SLC10A1 SLC10A6 SLC16A7 SLC30A2 SLC35C2 SLC35E1 SLC35E3 SLC39A2 SLC47A1 SVOP TLCD4 TLE1 TM4SF18 TMEM154 TMEM237 TMEM239 TMEM31 TMEM35A TMEM72 TMEM86B TMPPE TP53 TRIM27 UNC119	11 interacting genes: CLCA4 CTSA CYB561D2 FUNDC2 FXYD6 GET3 GYPA MIP SGTA SLC35A4 SMIM1
Entrez ID		53826	201799
HPRD ID		09456	08719
Ensembl ID		ENSG00000137726	ENSG00000170006
Uniprot IDs		A0A024R3J8 Q9H0Q3	D6R923 Q6P9G4
PDB IDs
Enriched GO Terms of Interacting Partners?
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