MKNK1 and RCN3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		MKNK1	RCN3
Description		MAPK interacting serine/threonine kinase 1	reticulocalbin 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Serine/threonine Kinase Activity Calmodulin-dependent Protein Kinase Activity Protein Binding Calmodulin Binding ATP Binding Calcium-dependent Protein Serine/threonine Kinase Activity Metal Ion Binding Protein Serine Kinase Activity	Calcium Ion Binding Protein Binding
	Biological Process	Regulation Of Translation Protein Phosphorylation Peptidyl-serine Phosphorylation Intracellular Signal Transduction Protein Autophosphorylation	Protein Secretion Positive Regulation Of Peptidase Activity Protein Transport Collagen Biosynthetic Process ERAD Pathway Surfactant Homeostasis Regulation Of Protein Kinase B Signaling Phospholipid Homeostasis Lung Epithelium Development
Pathways		Spry regulation of FGF signaling
Drugs		Fostamatinib
Diseases
GWAS		Schizophrenia ( 26198764) Triglyceride levels ( 31170924)	Apolipoprotein A1 levels ( 32203549) Fructosamine levels ( 29844224) Height ( 31562340) Hematocrit ( 32888494) Hematological and biochemical traits ( 20139978) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Mean spheric corpuscular volume ( 32888494) Schizophrenia ( 25056061) Total glycated albumin levels ( 29844224)
Interacting Genes		27 interacting genes: APP ATXN3 CREBBP CREM DDAH2 DNAJC7 EIF4E EIF4G1 EIF4G2 EIF4G3 FANCA HGS HIPK2 HSP90AB1 MAPK1 MAPK14 MAPK3 MBP PABPC4 PAK2 PHAX PLA2G4A PRKDC RCN3 SPRY2 TNIP2 UBE2D1	13 interacting genes: CCDC103 HID1 KLHL42 MBD3 MKNK1 MYO15B NAA10 PACRGL PCSK6 PRUNE2 STAT6 SUFU ZNF417
Entrez ID		8569	57333
HPRD ID		09468	17962
Ensembl ID		ENSG00000079277	ENSG00000142552
Uniprot IDs		A8K341 Q7Z319 Q9BUB5	Q96D15
PDB IDs		2HW6 2Y9Q 5WVD
Enriched GO Terms of Interacting Partners?
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