MKNK1 and PHAX

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		MKNK1	PHAX
Description		MAPK interacting serine/threonine kinase 1	phosphorylated adaptor for RNA export
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Nucleoplasm Centrosome Cytosol Cajal Body Neuronal Cell Body Ribonucleoprotein Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Calmodulin-dependent Protein Kinase Activity Protein Binding Calmodulin Binding ATP Binding Calcium-dependent Protein Serine/threonine Kinase Activity Metal Ion Binding Protein Serine Kinase Activity	RNA Binding Protein Binding Toxic Substance Binding MRNA Cap Binding Complex Binding
	Biological Process	Regulation Of Translation Protein Phosphorylation Peptidyl-serine Phosphorylation Intracellular Signal Transduction Protein Autophosphorylation	SnRNA Export From Nucleus Protein Transport RNA Stabilization
Pathways		Spry regulation of FGF signaling	snRNP Assembly RNA polymerase II transcribes snRNA genes
Drugs		Fostamatinib
Diseases
GWAS		Schizophrenia ( 26198764) Triglyceride levels ( 31170924)	Bipolar disorder ( 34099189) Colorectal cancer ( 30529582)
Interacting Genes		27 interacting genes: APP ATXN3 CREBBP CREM DDAH2 DNAJC7 EIF4E EIF4G1 EIF4G2 EIF4G3 FANCA HGS HIPK2 HSP90AB1 MAPK1 MAPK14 MAPK3 MBP PABPC4 PAK2 PHAX PLA2G4A PRKDC RCN3 SPRY2 TNIP2 UBE2D1	19 interacting genes: ASPSCR1 CDC42 GADD45G GRB7 ITIH1 MKNK1 NSFL1C OGT PDPK1 RAD23A RPS6KA1 STK3 TBCA TNFSF11 TULP3 UBXN2A VAV1 XPO1 ZWINT
Entrez ID		8569	51808
HPRD ID		09468	15122
Ensembl ID		ENSG00000079277	ENSG00000164902
Uniprot IDs		A8K341 Q7Z319 Q9BUB5	Q9H814
PDB IDs		2HW6 2Y9Q 5WVD	2XC7
Enriched GO Terms of Interacting Partners?
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