FBXL17 and USP25

  • Number of citations of the paper that reports this interaction (PubMedID 31560077)
  • 2
  • Data Source:
  • BioGRID (two hybrid)

FBXL17

USP25

Description F-box and leucine rich repeat protein 17 ubiquitin specific peptidase 25
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Bipolar disorder (body mass index interaction) ( 24322204)
  • Body mass index ( 25673413 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index in physically active individuals ( 28448500)
  • Carotid intima media thickness x smoking interaction ( 32117412)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Estimated glomerular filtration rate ( 31015462)
  • Experiencing mood swings ( 29500382)
  • Eye color ( 23118974)
  • General factor of neuroticism ( 30867560)
  • Hand grip strength ( 29691431)
  • Intelligence (MTAG) ( 29326435)
  • Intraocular pressure ( 29235454)
  • Irritable mood ( 29500382)
  • Mean corpuscular volume ( 32888494)
  • Metabolite levels ( 23823483)
  • Moderate-to-late spontaneous preterm birth ( 31194736)
  • Neurociticism ( 29500382)
  • Number of children ever born ( 27798627)
  • Pulse pressure ( 30224653)
  • Response to amphetamines ( 22952603)
  • smoking initiation in schizophrenia ( 33691233)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Weight ( 28552196)
  • Crohn's disease ( 25489960)
  • Metabolite levels ( 23823483)
  • Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269)
  • Panic disorder ( 19165232)
  • Parkinson's disease ( 21738487)
  • QRS complex (12-leadsum) ( 27659466)
  • Serum alkaline phosphatase levels ( 33547301)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes 39 interacting genes: ACSBG2 AK9 C21orf91 CCSER1 CFAP58 CLPX COG2 ETFA FILIP1L HADH IDO1 IFT46 KBTBD8 KEAP1 KLHL12 KLHL7 MED14 METAP2 OLR1 PCCB PHF7 PPP3CB PRMT1 PSME4 PXYLP1 RLF SCG5 SCPEP1 SRBD1 SUFU TASP1 TGFBI TMEM126A TMOD1 TPP2 UAP1 USP25 ZMYM2 ZNF350 22 interacting genes: ACTA1 FBXL17 FLNC GAPDH MAGEB4 MID2 MT2A NGEF PUS10 RAD23A RAD23B SENP1 SKIL SUMO1 SUMO2 SUMO3 SYK TMEM43 TNKS UBC UBE2I ZNF426
Entrez ID 64839 29761
HPRD ID 10950 05296
Ensembl ID ENSG00000145743 ENSG00000155313
Uniprot IDs Q9UF56 Q9UHP3
PDB IDs 6W66 6WCQ 2MUX 5GP7 5O71 6H4J 6H4K 6HEL 6HEM
Enriched GO Terms of Interacting Partners?
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