FBXL17 and METAP2

  • Number of citations of the paper that reports this interaction (PubMedID 31560077)
  • 2
  • Data Source:
  • BioGRID (two hybrid)

FBXL17

METAP2

Description F-box and leucine rich repeat protein 17 methionyl aminopeptidase 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Bipolar disorder (body mass index interaction) ( 24322204)
  • Body mass index ( 25673413 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index in physically active individuals ( 28448500)
  • Carotid intima media thickness x smoking interaction ( 32117412)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Estimated glomerular filtration rate ( 31015462)
  • Experiencing mood swings ( 29500382)
  • Eye color ( 23118974)
  • General factor of neuroticism ( 30867560)
  • Hand grip strength ( 29691431)
  • Intelligence (MTAG) ( 29326435)
  • Intraocular pressure ( 29235454)
  • Irritable mood ( 29500382)
  • Mean corpuscular volume ( 32888494)
  • Metabolite levels ( 23823483)
  • Moderate-to-late spontaneous preterm birth ( 31194736)
  • Neurociticism ( 29500382)
  • Number of children ever born ( 27798627)
  • Pulse pressure ( 30224653)
  • Response to amphetamines ( 22952603)
  • smoking initiation in schizophrenia ( 33691233)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Weight ( 28552196)
  • Blood protein levels ( 30072576)
  • C-reactive protein levels ( 30388399)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • Immature fraction of reticulocytes ( 27863252)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
  • Metabolite levels ( 23823483)
  • Reticulocyte count ( 32888494)
Interacting Genes 39 interacting genes: ACSBG2 AK9 C21orf91 CCSER1 CFAP58 CLPX COG2 ETFA FILIP1L HADH IDO1 IFT46 KBTBD8 KEAP1 KLHL12 KLHL7 MED14 METAP2 OLR1 PCCB PHF7 PPP3CB PRMT1 PSME4 PXYLP1 RLF SCG5 SCPEP1 SRBD1 SUFU TASP1 TGFBI TMEM126A TMOD1 TPP2 UAP1 USP25 ZMYM2 ZNF350 14 interacting genes: APP CALM1 CDC42 EIF2AK2 EIF2S3 FBXL17 HMGA1 MAPK1 MAPK3 OGT PJA1 RAC1 S100A4 YWHAE
Entrez ID 64839 10988
HPRD ID 10950 03522
Ensembl ID ENSG00000145743 ENSG00000111142
Uniprot IDs Q9UF56 A0A140VJE3 F8VQZ7 P50579
PDB IDs 6W66 6WCQ 1B59 1B6A 1BN5 1BOA 1KQ0 1KQ9 1QZY 1R58 1R5G 1R5H 1YW7 1YW8 1YW9 2ADU 2EA2 2EA4 2GA2 2OAZ 5CLS 5D6E 5D6F 5JFR 5JHU 5JI6 5LYW 5LYX 6QED 6QEF 6QEG 6QEH 6QEI 6QEJ 7A12 7A13 7A14 7A15 7A16
Enriched GO Terms of Interacting Partners?
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