PLEKHB1 and RAP1GDS1

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

PLEKHB1

RAP1GDS1

Description pleckstrin homology domain containing B1 Rap1 GTPase-GDP dissociation stimulator 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Dimensional psychopathology (Cognitive) ( 29496196)
  • Glucose homeostasis traits ( 25524916)
  • Hand grip strength ( 27325353)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Biochemical measures ( 19260141)
  • Response to fenofibrate (total cholesterol levels) ( 27002377)
  • Suicidality in mood disorders ( 33783297)
  • Suicide attempt severity in mood disorders ( 33783297)
Interacting Genes 13 interacting genes: ACVR1 ATXN1 BAG3 BMPR1B C10orf55 CCR8 GLIS2 GNGT1 RAP1GDS1 SMAD1 TGFBR1 VENTX ZDHHC17 28 interacting genes: ABCB7 ANTXR2 CDC42 DIRAS1 DIRAS2 DOC2A EGFR HRAS KIFAP3 KRAS LEF1 MBIP MED28 NRAS OGT PLEKHB1 PTPRF PUF60 RAB6B RAC1 RAP1A RAP2B RAP2C RHOA RNF19B RRAS RRAS2 ZNF451
Entrez ID 58473 5910
HPRD ID 09630 11763
Ensembl ID ENSG00000021300 ENSG00000138698
Uniprot IDs A0A024R5H7 A0A024R5H9 A0A024R5J2 Q9UF11 B3KNU0 P52306 Q6U7G8
PDB IDs 5XGC 5ZHX
Enriched GO Terms of Interacting Partners?
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