RAP1GDS1 and DIRAS1

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

		RAP1GDS1	DIRAS1
Description		Rap1 GTPase-GDP dissociation stimulator 1	DIRAS family GTPase 1
Image
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Cytosol Extracellular Exosome	Plasma Membrane
	Molecular Function	GTPase Activator Activity Protein Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Mitogen-activated Protein Kinase Binding
	Biological Process	Vascular Associated Smooth Muscle Contraction Myosin Filament Assembly Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Positive Regulation Of GTPase Activity Positive Regulation Of Mitochondrial Calcium Ion Concentration	Signal Transduction Positive Regulation Of MAP Kinase Activity
Pathways		RHOT2 GTPase cycle RHOT1 GTPase cycle
Drugs
Diseases
GWAS		Biochemical measures ( 19260141) Response to fenofibrate (total cholesterol levels) ( 27002377) Suicidality in mood disorders ( 33783297) Suicide attempt severity in mood disorders ( 33783297)	Eosinophil counts ( 32888494)
Interacting Genes		28 interacting genes: ABCB7 ANTXR2 CDC42 DIRAS1 DIRAS2 DOC2A EGFR HRAS KIFAP3 KRAS LEF1 MBIP MED28 NRAS OGT PLEKHB1 PTPRF PUF60 RAB6B RAC1 RAP1A RAP2B RAP2C RHOA RNF19B RRAS RRAS2 ZNF451	4 interacting genes: APP PPP1R13B RAP1GDS1 TP53BP2
Entrez ID		5910	148252
HPRD ID		11763	09710
Ensembl ID		ENSG00000138698	ENSG00000176490
Uniprot IDs		B3KNU0 P52306 Q6U7G8	O95057
PDB IDs		5XGC 5ZHX	2GF0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?