ATXN7L3 and USP22

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		ATXN7L3	USP22
Description		ataxin 7 like 3	ubiquitin specific peptidase 22
Image			No pdb structure
GO Annotations	Cellular Component	SAGA Complex Nucleus DUBm Complex	SAGA Complex Nucleoplasm
	Molecular Function	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Nuclear Receptor Coactivator Activity	Transcription Coactivator Activity Thiol-dependent Deubiquitinase Protein Binding Zinc Ion Binding H4 Histone Acetyltransferase Activity Enzyme Binding Nuclear Receptor Coactivator Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Histone Monoubiquitination Histone Deubiquitination Positive Regulation Of Transcription, DNA-templated	Ubiquitin-dependent Protein Catabolic Process Cell Cycle Embryo Development Ending In Birth Or Egg Hatching Histone Ubiquitination Histone Deubiquitination Protein Deubiquitination Histone H4 Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Mitotic Cell Cycle
Pathways		HATs acetylate histones	HATs acetylate histones Ub-specific processing proteases
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Height ( 31562340)	Body mass index ( 26426971) Mosquito bite size ( 28199695)
Interacting Genes		12 interacting genes: APP DCAKD ENY2 H2AC20 H2BC21 PICK1 SECISBP2 SERTAD1 UBC UCHL3 USP22 USP6	17 interacting genes: AASDHPPT ATXN7 ATXN7L3 B9D1 BAG4 H2AC20 H2BC21 HEXA MRPL10 MRPL44 MTUS2 PSME1 PTGS2 RCAN1 SCFD1 SIRT1 UBC
Entrez ID		56970	23326
HPRD ID		12507	19411
Ensembl ID		ENSG00000087152	ENSG00000124422
Uniprot IDs		Q14CW9	Q9UPT9
PDB IDs		2KKT
Enriched GO Terms of Interacting Partners?
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