USP22 and ATXN7L3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		USP22	ATXN7L3
Description		ubiquitin specific peptidase 22	ataxin 7 like 3
Image		No pdb structure
GO Annotations	Cellular Component	SAGA Complex Nucleoplasm	SAGA Complex Nucleus DUBm Complex
	Molecular Function	Transcription Coactivator Activity Thiol-dependent Deubiquitinase Protein Binding Zinc Ion Binding H4 Histone Acetyltransferase Activity Enzyme Binding Nuclear Receptor Coactivator Activity	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Nuclear Receptor Coactivator Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Cell Cycle Embryo Development Ending In Birth Or Egg Hatching Histone Ubiquitination Histone Deubiquitination Protein Deubiquitination Histone H4 Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Mitotic Cell Cycle	Regulation Of Transcription By RNA Polymerase II Histone Monoubiquitination Histone Deubiquitination Positive Regulation Of Transcription, DNA-templated
Pathways		HATs acetylate histones Ub-specific processing proteases	HATs acetylate histones
Drugs
Diseases
GWAS		Body mass index ( 26426971) Mosquito bite size ( 28199695)	Bipolar disorder ( 31043756) Height ( 31562340)
Interacting Genes		17 interacting genes: AASDHPPT ATXN7 ATXN7L3 B9D1 BAG4 H2AC20 H2BC21 HEXA MRPL10 MRPL44 MTUS2 PSME1 PTGS2 RCAN1 SCFD1 SIRT1 UBC	12 interacting genes: APP DCAKD ENY2 H2AC20 H2BC21 PICK1 SECISBP2 SERTAD1 UBC UCHL3 USP22 USP6
Entrez ID		23326	56970
HPRD ID		19411	12507
Ensembl ID		ENSG00000124422	ENSG00000087152
Uniprot IDs		Q9UPT9	Q14CW9
PDB IDs			2KKT
Enriched GO Terms of Interacting Partners?
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