ATXN7L3 and ENY2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		ATXN7L3	ENY2
Description		ataxin 7 like 3	ENY2 transcription and export complex 2 subunit
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GO Annotations	Cellular Component	SAGA Complex Nucleus DUBm Complex	SAGA Complex Nucleoplasm Mitochondrion Nuclear Pore Nuclear Basket Transcription Export Complex 2 DUBm Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Nuclear Receptor Coactivator Activity	Chromatin Binding Transcription Coactivator Activity Protein Binding Nuclear Receptor Coactivator Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Histone Monoubiquitination Histone Deubiquitination Positive Regulation Of Transcription, DNA-templated	Regulation Of Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Protein Transport Histone Deubiquitination Poly(A)+ MRNA Export From Nucleus Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Pathways		HATs acetylate histones	HATs acetylate histones
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Height ( 31562340)	Metabolite levels ( 23823483) Multiple system atrophy (pathologically confirmed) ( 27629089) Night sleep phenotypes ( 27126917)
Interacting Genes		12 interacting genes: APP DCAKD ENY2 H2AC20 H2BC21 PICK1 SECISBP2 SERTAD1 UBC UCHL3 USP22 USP6	7 interacting genes: APP ATXN7L3 ATXN7L3B C11orf49 HNRNPA2B1 MCM3AP UFL1
Entrez ID		56970	56943
HPRD ID		12507	13121
Ensembl ID		ENSG00000087152	ENSG00000120533
Uniprot IDs		Q14CW9	A0A024R9D9 Q9NPA8
PDB IDs		2KKT	4DHX
Enriched GO Terms of Interacting Partners?
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