ATXN7L3 and USP6

Number of citations of the paper that reports this interaction (PubMedID 16713569)
337

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATXN7L3	USP6
Description		ataxin 7 like 3	ubiquitin specific peptidase 6
Image			No pdb structure
GO Annotations	Cellular Component	SAGA Complex Nucleus DUBm Complex	Cytoplasm Lysosome Plasma Membrane Recycling Endosome
	Molecular Function	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Nuclear Receptor Coactivator Activity	Nucleic Acid Binding Cysteine-type Endopeptidase Activity Thiol-dependent Deubiquitinase GTPase Activator Activity Protein Binding Calmodulin Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Histone Monoubiquitination Histone Deubiquitination Positive Regulation Of Transcription, DNA-templated	Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Intracellular Protein Transport Protein Deubiquitination Regulation Of Vesicle-mediated Transport Activation Of GTPase Activity
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Height ( 31562340)	PEG-asparaginase hypersensitivity without enzyme activity in childhood acute lymphoblastic leukaemia ( 30450575)
Interacting Genes		12 interacting genes: APP DCAKD ENY2 H2AC20 H2BC21 PICK1 SECISBP2 SERTAD1 UBC UCHL3 USP22 USP6	18 interacting genes: ANKRD11 ANKRD44 APP ATXN7L3 CABP2 CALM2 CDC42 EXOSC8 JAK1 JUN MDFI MYL2 RAB33B RAC1 RIPPLY1 TFIP11 UBC ZNF76
Entrez ID		56970	9098
HPRD ID		12507	06827
Ensembl ID		ENSG00000087152	ENSG00000129204
Uniprot IDs		Q14CW9	P35125
PDB IDs		2KKT
Enriched GO Terms of Interacting Partners?
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