NGLY1 and RAD23B

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (biochemical, affinity chromatography technology, two hybrid)
HPRD (in vitro)

		NGLY1	RAD23B
Description		N-glycanase 1	RAD23 homolog B, nucleotide excision repair protein
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Proteasome Complex Nucleus Nucleoplasm Cytosol XPC Complex
	Molecular Function	Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine Amidase Activity Protein Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Damaged DNA Binding Single-stranded DNA Binding Protein Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Proteasome Binding
	Biological Process	Protein Folding Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Glycoprotein Catabolic Process Protein Deglycosylation ER-associated Misfolded Protein Catabolic Process	Nucleotide-excision Repair, DNA Damage Recognition Nucleotide-excision Repair Spermatogenesis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Embryonic Organ Development Cellular Response To Interleukin-7
Pathways		N-glycan trimming in the ER and Calnexin/Calreticulin cycle	N-glycan trimming in the ER and Calnexin/Calreticulin cycle Josephin domain DUBs DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER
Drugs
Diseases
GWAS			Body mass index ( 20966902) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 21263130) Chronotype ( 30696823) Cutaneous malignant melanoma ( 26237428) Melanoma ( 28212542) Prostate cancer ( 23023329)
Interacting Genes		25 interacting genes: APP BICRAL FAF1 GJB2 GRM7 GUCD1 LIMD1 MAP3K2 NPAS2 NSFL1C OPA3 PAX5 PAX6 PROC RAD23A RAD23B SH3BP1 SRPK2 TCF12 TRAFD1 TRIM54 UBQLN1 UBXN2B VCP VMAC	30 interacting genes: ADRM1 ATXN3 CALM1 DBI DEAF1 HIP1 HMGB1 MKRN1 MLH1 MPG NGLY1 OGT PAQR3 PAX3 PNMA5 POU6F2 PSMC2 PSMD4 PUF60 RPA1 RSC1A1 TAX1BP1 TDG UBA2 UBB UBC UBE3A USP25 XPC ZFAND5
Entrez ID		55768	5887
HPRD ID		10118	06772
Ensembl ID		ENSG00000151092	ENSG00000119318
Uniprot IDs		Q96IV0	B7Z4W4 P54727
PDB IDs		2CCQ 2CM0	1P1A 1PVE 1UEL
Enriched GO Terms of Interacting Partners?
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