NGLY1 and NSFL1C

Number of citations of the paper that reports this interaction (PubMedID 16807242)
33

Data Source:
BioGRID (pull down)

		NGLY1	NSFL1C
Description		N-glycanase 1	NSFL1 cofactor
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus Nucleoplasm Chromosome Golgi Stack Cytosol Plasma Membrane Spindle Pole Centrosome Intermediate Filament Cytoskeleton VCP-NSFL1C Complex
	Molecular Function	Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine Amidase Activity Protein Binding Metal Ion Binding	Protein Binding Phospholipid Binding Ubiquitin Binding ATPase Binding
	Biological Process	Protein Folding Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Glycoprotein Catabolic Process Protein Deglycosylation ER-associated Misfolded Protein Catabolic Process	Autophagosome Assembly Establishment Of Mitotic Spindle Orientation Golgi Organization Nuclear Membrane Reassembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Mitotic Centrosome Separation Membrane Fusion Negative Regulation Of Protein Localization To Centrosome
Pathways		N-glycan trimming in the ER and Calnexin/Calreticulin cycle	RHOH GTPase cycle
Drugs
Diseases
GWAS
Interacting Genes		25 interacting genes: APP BICRAL FAF1 GJB2 GRM7 GUCD1 LIMD1 MAP3K2 NPAS2 NSFL1C OPA3 PAX5 PAX6 PROC RAD23A RAD23B SH3BP1 SRPK2 TCF12 TRAFD1 TRIM54 UBQLN1 UBXN2B VCP VMAC	17 interacting genes: ANP32A CDK1 DBI FAM32A FASTKD5 GLMN GSK3B LIPE NGLY1 PHAX PRKACA RPL22 SRP14 STX5 TARDBP UBC VCP
Entrez ID		55768	55968
HPRD ID		10118	09425
Ensembl ID		ENSG00000151092	ENSG00000088833
Uniprot IDs		Q96IV0	Q53FE8 Q9UNZ2
PDB IDs		2CCQ 2CM0	1SS6
Enriched GO Terms of Interacting Partners?
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