TREM2 and APOE

  • Number of citations of the paper that reports this interaction (PubMedID 27477018)
  • 227

TREM2

APOE

Description triggering receptor expressed on myeloid cells 2 apolipoprotein E
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease ( 23150908)
  • Alzheimer's disease (late onset) ( 28714976)
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Blood protein levels ( 30072576)
  • C-reactive protein ( 22939635)
  • Family history of Alzheimer's disease ( 30617256)
  • Supraventricular ectopy ( 29618737)
Interacting Genes 10 interacting genes: APOA1 APOA2 APOB APOE CLU GH1 NRN1L SCGB2A2 TYROBP UNC5B 65 interacting genes: A2M ALB ANKH APOC2 APOC4 APP ARFGAP1 CD1D CD79A CDC37 CEACAM1 CNTF CSNK2A1 CST1 CTSB CYP2C18 CYP2C8 ECSIT ELAVL1 EPN2 FARSA FBXL12 FOXG1 FXYD7 GCDH HSP90AA1 HTRA1 IFIT3 IFIT5 IQSEC1 LCAT LDLR LINC02582 LONP1 LOXL4 LRP1 LRP2 LRP8 MAP2 MAPT MAST1 MID1IP1 NEFM NOS3 PCMT1 PDCD4 PLEKHA6 PLTP PRAM1 PRDX2 PRNP PSEN1 RHEB RNF32 RPL4 SCARB1 SNCA SORL1 ST13 TIMM29 TREM2 TYRO3 VLDLR ZBP1 ZNF558
Entrez ID 54209 348
HPRD ID 05473 00135
Ensembl ID ENSG00000095970 ENSG00000130203
Uniprot IDs Q5TCX1 Q9NZC2 A0A0S2Z3D5 P02649
PDB IDs 5ELI 5UD7 5UD8 6B8O 6XDS 6Y6C 6YMQ 6YYE 6Z0G 6Z0H 6Z0I 1B68 1BZ4 1EA8 1GS9 1H7I 1LE2 1LE4 1LPE 1NFN 1NFO 1OEF 1OEG 1OR2 1OR3 2KC3 2KNY 2L7B 6IWB 6NCN 6NCO
Enriched GO Terms of Interacting Partners?
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