APOE and CYP2C18

  • Number of citations of the paper that reports this interaction (PubMedID 21163940)
  • 36
  • Data Source:
  • BioGRID (two hybrid)

APOE

CYP2C18

Description apolipoprotein E cytochrome P450 family 2 subfamily C member 18
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acenocoumarol maintenance dosage ( 19578179)
  • Clopidogrel active metabolite levels ( 28207573)
  • Common carotid intima-media thickness in HIV negative individuals ( 29206233)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
  • Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102)
  • Red cell distribution width ( 32888494)
  • Response to clopidogrel therapy ( 28207573 19706858)
  • Serum alkaline phosphatase levels ( 33547301)
  • Serum metabolite levels ( 23093944)
  • Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122)
  • Warfarin maintenance dose ( 23755828)
  • Warfarin maintenance dose (adjusted for clinical factors) ( 28686080)
Interacting Genes 65 interacting genes: A2M ALB ANKH APOC2 APOC4 APP ARFGAP1 CD1D CD79A CDC37 CEACAM1 CNTF CSNK2A1 CST1 CTSB CYP2C18 CYP2C8 ECSIT ELAVL1 EPN2 FARSA FBXL12 FOXG1 FXYD7 GCDH HSP90AA1 HTRA1 IFIT3 IFIT5 IQSEC1 LCAT LDLR LINC02582 LONP1 LOXL4 LRP1 LRP2 LRP8 MAP2 MAPT MAST1 MID1IP1 NEFM NOS3 PCMT1 PDCD4 PLEKHA6 PLTP PRAM1 PRDX2 PRNP PSEN1 RHEB RNF32 RPL4 SCARB1 SNCA SORL1 ST13 TIMM29 TREM2 TYRO3 VLDLR ZBP1 ZNF558 6 interacting genes: A2M APOE ECSIT KMT2E PSEN1 SDC2
Entrez ID 348 1562
HPRD ID 00135 03085
Ensembl ID ENSG00000130203 ENSG00000108242
Uniprot IDs A0A0S2Z3D5 P02649 P33260 Q7Z348
PDB IDs 1B68 1BZ4 1EA8 1GS9 1H7I 1LE2 1LE4 1LPE 1NFN 1NFO 1OEF 1OEG 1OR2 1OR3 2KC3 2KNY 2L7B 6IWB 6NCN 6NCO 2CIK 2H6P
Enriched GO Terms of Interacting Partners?
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