LIG1 and CDYL2

Number of citations of the paper that reports this interaction (PubMedID 33097091)
0

Data Source:
BioGRID (unspecified method)

		LIG1	CDYL2
Description		DNA ligase 1	chromodomain Y like 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Intracellular Membrane-bounded Organelle	Nucleus
	Molecular Function	DNA Binding DNA Ligase Activity DNA Ligase (ATP) Activity ATP Binding Metal Ion Binding	Transcription Corepressor Activity Catalytic Activity Protein Binding Methylated Histone Binding
	Biological Process	DNA Ligation Lagging Strand Elongation DNA Repair Base-excision Repair Base-excision Repair, Gap-filling Mismatch Repair Anatomical Structure Morphogenesis V(D)J Recombination Cell Division DNA Biosynthetic Process Okazaki Fragment Processing Involved In Mitotic DNA Replication	Negative Regulation Of Transcription, DNA-templated
Pathways		POLB-Dependent Long Patch Base Excision Repair Early Phase of HIV Life Cycle Processive synthesis on the C-strand of the telomere Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) PCNA-Dependent Long Patch Base Excision Repair Gap-filling DNA repair synthesis and ligation in GG-NER Gap-filling DNA repair synthesis and ligation in TC-NER Processive synthesis on the lagging strand
Drugs		Bleomycin
Diseases
GWAS			Breast cancer ( 29059683 23535729) Inflammatory bowel disease ( 27569725) Interleukin-10 levels ( 22205395) Liver enzyme levels (alkaline phosphatase) ( 33972514) Metabolite levels ( 23823483) Prostate cancer ( 31748686) Pulse pressure ( 30224653) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		19 interacting genes: CBX3 CDY1 CDYL CDYL2 CSNK2A1 DCAF7 EHMT1 EHMT2 HSPB1 INPP1 L3MBTL3 MIER1 MRE11 PCNA PHF20 PRKCB RGS2 TUBB3 UHRF1	11 interacting genes: DVL3 H3-4 H3C1 HINFP HSF2BP LIG1 LMO3 NXF1 PRMT5 SPANXN2 ZBTB9
Entrez ID		3978	124359
HPRD ID		00534	10819
Ensembl ID		ENSG00000105486	ENSG00000166446
Uniprot IDs		B4DM52 F5GZ28 P18858	Q8N8U2
PDB IDs		1X9N 5YY9 6P09 6P0A 6P0B 6P0C 6P0D 6P0E 6Q1V 7KR3 7KR4 7L34 7L35	2MJ8 4HAE 5JJZ 6V2D 6V2H 6V3N 6V8W
Enriched GO Terms of Interacting Partners?
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