LIG1 and CDYL

Number of citations of the paper that reports this interaction (PubMedID 33097091)
0

Data Source:
BioGRID (unspecified method)

		LIG1	CDYL
Description		DNA ligase 1	chromodomain Y like
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Intracellular Membrane-bounded Organelle	Nucleus Chromosome Cytoplasm Nuclear Speck
	Molecular Function	DNA Binding DNA Ligase Activity DNA Ligase (ATP) Activity ATP Binding Metal Ion Binding	Chromatin Binding Transcription Corepressor Activity Protein Binding Protein-macromolecule Adaptor Activity Methylated Histone Binding Crotonyl-CoA Hydratase Activity
	Biological Process	DNA Ligation Lagging Strand Elongation DNA Repair Base-excision Repair Base-excision Repair, Gap-filling Mismatch Repair Anatomical Structure Morphogenesis V(D)J Recombination Cell Division DNA Biosynthetic Process Okazaki Fragment Processing Involved In Mitotic DNA Replication	Spermatogenesis Spermatid Development Negative Regulation Of Transcription, DNA-templated Random Inactivation Of X Chromosome Negative Regulation Of Peptidyl-lysine Crotonylation
Pathways		POLB-Dependent Long Patch Base Excision Repair Early Phase of HIV Life Cycle Processive synthesis on the C-strand of the telomere Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) PCNA-Dependent Long Patch Base Excision Repair Gap-filling DNA repair synthesis and ligation in GG-NER Gap-filling DNA repair synthesis and ligation in TC-NER Processive synthesis on the lagging strand
Drugs		Bleomycin
Diseases
GWAS			Age at smoking initiation in chronic obstructive pulmonary disease ( 21685187) Body mass index ( 28552196) Cellular nuclear factor (erythroid-derived 2)-like 2 levels ( 30767168) Red cell distribution width ( 32888494) Response to ketogenic dietary therapies in epilepsy ( 30009487) Weight ( 28552196)
Interacting Genes		19 interacting genes: CBX3 CDY1 CDYL CDYL2 CSNK2A1 DCAF7 EHMT1 EHMT2 HSPB1 INPP1 L3MBTL3 MIER1 MRE11 PCNA PHF20 PRKCB RGS2 TUBB3 UHRF1	9 interacting genes: FXR1 H3-4 H3C1 HDAC1 HDAC2 HTRA1 LIG1 REST TTC9C
Entrez ID		3978	9425
HPRD ID		00534	04803
Ensembl ID		ENSG00000105486	ENSG00000153046
Uniprot IDs		B4DM52 F5GZ28 P18858	Q9Y232
PDB IDs		1X9N 5YY9 6P09 6P0A 6P0B 6P0C 6P0D 6P0E 6Q1V 7KR3 7KR4 7L34 7L35	2DNT 2GTR
Enriched GO Terms of Interacting Partners?
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