LIG1 and PHF20

Number of citations of the paper that reports this interaction (PubMedID 33097091)
0

Data Source:
BioGRID (unspecified method)

		LIG1	PHF20
Description		DNA ligase 1	PHD finger protein 20
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Intracellular Membrane-bounded Organelle	Histone Acetyltransferase Complex Nucleoplasm Cytosol Nuclear Membrane NSL Complex MLL1 Complex
	Molecular Function	DNA Binding DNA Ligase Activity DNA Ligase (ATP) Activity ATP Binding Metal Ion Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	DNA Ligation Lagging Strand Elongation DNA Repair Base-excision Repair Base-excision Repair, Gap-filling Mismatch Repair Anatomical Structure Morphogenesis V(D)J Recombination Cell Division DNA Biosynthetic Process Okazaki Fragment Processing Involved In Mitotic DNA Replication	Regulation Of Transcription By RNA Polymerase II Histone Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation
Pathways		POLB-Dependent Long Patch Base Excision Repair Early Phase of HIV Life Cycle Processive synthesis on the C-strand of the telomere Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) PCNA-Dependent Long Patch Base Excision Repair Gap-filling DNA repair synthesis and ligation in GG-NER Gap-filling DNA repair synthesis and ligation in TC-NER Processive synthesis on the lagging strand	HATs acetylate histones Regulation of TP53 Degradation Regulation of TP53 Activity through Association with Co-factors Stabilization of p53
Drugs		Bleomycin
Diseases
GWAS			Blood protein levels ( 28240269) General cognitive ability ( 29844566) Height ( 28552196 25282103) Hip circumference adjusted for BMI ( 34021172) Mean platelet volume ( 32888494) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		19 interacting genes: CBX3 CDY1 CDYL CDYL2 CSNK2A1 DCAF7 EHMT1 EHMT2 HSPB1 INPP1 L3MBTL3 MIER1 MRE11 PCNA PHF20 PRKCB RGS2 TUBB3 UHRF1	4 interacting genes: CEP250 H3C1 H4C1 LIG1
Entrez ID		3978	51230
HPRD ID		00534	08514
Ensembl ID		ENSG00000105486	ENSG00000025293
Uniprot IDs		B4DM52 F5GZ28 P18858	Q9BVI0
PDB IDs		1X9N 5YY9 6P09 6P0A 6P0B 6P0C 6P0D 6P0E 6Q1V 7KR3 7KR4 7L34 7L35	2LDM 3P8D 3Q1J 3QII 3SD4 5TAB 5TBN
Enriched GO Terms of Interacting Partners?
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