A1CF and PLEKHG4

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

A1CF

PLEKHG4

Description APOBEC1 complementation factor pleckstrin homology and RhoGEF domain containing G4
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • 3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134)
  • Colorectal cancer or advanced adenoma ( 30510241)
  • Estimated glomerular filtration rate ( 31152163 31015462 31451708)
  • Estimated glomerular filtration rate in non-diabetics ( 31451708)
  • Gamma glutamyl transferase levels ( 33339817)
  • Glomerular filtration rate (creatinine) ( 28452372)
  • Glomerular filtration rate in non diabetics (creatinine) ( 26831199)
  • Interferon alpha levels in systemic lupus erythematosus ( 25338677)
  • LDL cholesterol ( 30275531)
  • Low density lipoprotein cholesterol levels ( 32154731)
  • Narcolepsy with cataplexy ( 25986216)
  • Serum uric acid levels ( 30993211)
  • Total cholesterol levels ( 30275531)
  • Triglyceride levels ( 32154731)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglycerides ( 30275531)
  • Urate levels ( 31985003 31578528 23263486)
  • Urate levels in lean individuals ( 25811787)
Interacting Genes 26 interacting genes: APOBEC1 C19orf54 C9orf24 CAVIN2 CELF2 CYSRT1 DOK3 ECM1 EIF4G1 FHL2 FHL3 HSPB2 HSPB2-C11orf52 KHSRP KLHDC7B KRT31 KRT34 METTL27 OIP5 PLEKHG4 POGZ REL RIMBP3C SYNCRIP TNPO2 TRAF1 66 interacting genes: A1CF ARHGEF5 ARMC7 BEX2 CCDC120 CCDC187 CDC42 CDKN2C CHIC2 COIL DCUN1D5 DPPA3 DTX2 DUSP13 FAM161A FGD2 GATA3 GCM2 GSTZ1 HCK HOXB9 HOXC8 KRT3 KRT75 MALSU1 MATR3 MDFI METAP1 MSRB3 MTA1 MYEF2 MYOZ1 NATD1 OTX1 PFKFB1 PKP2 PLA2G15 PPP1R32 PRPF18 PRPF31 PSMB1 RHOA RIN1 SAXO1 SETD5 SH2D4A SHISA6 SIX1 SMCP SMG9 TBC1D22B TBX18 TEKT3 TENT5D TFAP2D TFG TRIM55 TRIM63 TSSK3 TTC23 USP2 VPS37C ZCCHC14 ZNF148 ZNF319 ZNF648
Entrez ID 29974 25894
HPRD ID 10627 10890
Ensembl ID ENSG00000148584 ENSG00000196155
Uniprot IDs A0A024QZI9 A0A024QZJ5 A0A024QZM7 B4E1E3 F8W9F8 Q9NQ94 A0A024R6X4 Q58EX7
PDB IDs 2CPD
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?