A1CF and HSPB2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		A1CF	HSPB2
Description		APOBEC1 complementation factor	heat shock protein family B (small) member 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Apolipoprotein B MRNA Editing Enzyme Complex	Nucleus Cytoplasm Cytosol
	Molecular Function	RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding MRNA Binding Protein Binding	Structural Constituent Of Eye Lens Protein Binding Enzyme Activator Activity
	Biological Process	MRNA Processing Embryo Implantation MRNA Localization Resulting In Posttranscriptional Regulation Of Gene Expression Cytidine To Uridine Editing MRNA Modification Protein Stabilization	Response To Unfolded Protein Regulation Of Catalytic Activity
Pathways		mRNA Editing: C to U Conversion Formation of the Editosome
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Colorectal cancer or advanced adenoma ( 30510241) Estimated glomerular filtration rate ( 31152163 31015462 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Gamma glutamyl transferase levels ( 33339817) Glomerular filtration rate (creatinine) ( 28452372) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Interferon alpha levels in systemic lupus erythematosus ( 25338677) LDL cholesterol ( 30275531) Low density lipoprotein cholesterol levels ( 32154731) Narcolepsy with cataplexy ( 25986216) Serum uric acid levels ( 30993211) Total cholesterol levels ( 30275531) Triglyceride levels ( 32154731) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglycerides ( 30275531) Urate levels ( 31985003 31578528 23263486) Urate levels in lean individuals ( 25811787)	Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		26 interacting genes: APOBEC1 C19orf54 C9orf24 CAVIN2 CELF2 CYSRT1 DOK3 ECM1 EIF4G1 FHL2 FHL3 HSPB2 HSPB2-C11orf52 KHSRP KLHDC7B KRT31 KRT34 METTL27 OIP5 PLEKHG4 POGZ REL RIMBP3C SYNCRIP TNPO2 TRAF1	110 interacting genes: A1CF A2M ABCC9 ABCD4 ACAA2 ACTA1 ACTB ACTC1 ACTG1 AGAP11 ALDH2 ALDOA ASAH1 ATM ATP5F1A ATP6V1E1 B2M BAG3 BEX2 BEX4 BGN BICRAL C1QA CAPZA2 CEP19 CKM CLK4 CMYA5 CRYAA CRYAB CRYGC CTSB CTSD CYP1B1 DCTN1 DCTN6 DDIT4 DDX10 DMPK DUSP1 EEF1A1 EIF4A2 ENKD1 ENO1 ENO3 ETFA FHL2 FLNC GAPDH GARS1 HADHB HNRNPD HOXB9 HSPB3 HSPB8 KANK2 LGALS1 LMO1 LMO3 MAPKAPK5 MB MCCC2 MDH1 MISP MLF2 MT-CO1 MT-CO2 MT-CO3 MYBPC3 MYH6 MYOM2 MYOZ2 NARS1 NDUFA13 NDUFA6 NT5DC2 PARVA PATZ1 PGM1 PKP2 POGZ PPM1K PRR35 RFPL3 RPL11 RPL36A RPL36AL RPS11 RPS6KA5 RYR2 SDF2 SDHA SLC2A1 SNCA SNU13 SNX18 TATDN1 TCAP THEMIS2 THUMPD2 TLX3 TNNI3 TTN TXNIP UBL5 VEZF1 WDR1 WWOX YPEL3 ZNF335
Entrez ID		29974	3316
HPRD ID		10627	03712
Ensembl ID		ENSG00000148584	ENSG00000170276
Uniprot IDs		A0A024QZI9 A0A024QZJ5 A0A024QZM7 B4E1E3 F8W9F8 Q9NQ94	A8KAH6 Q16082
PDB IDs		2CPD	6F2R
Enriched GO Terms of Interacting Partners?
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