PLEKHG4 and ARHGEF5

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

PLEKHG4

ARHGEF5

Description pleckstrin homology and RhoGEF domain containing G4 Rho guanine nucleotide exchange factor 5
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Breast cancer ( 23535729)
  • Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226)
  • Gut microbiota relative abundance (Parabacteroides) ( 33208821)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes 66 interacting genes: A1CF ARHGEF5 ARMC7 BEX2 CCDC120 CCDC187 CDC42 CDKN2C CHIC2 COIL DCUN1D5 DPPA3 DTX2 DUSP13 FAM161A FGD2 GATA3 GCM2 GSTZ1 HCK HOXB9 HOXC8 KRT3 KRT75 MALSU1 MATR3 MDFI METAP1 MSRB3 MTA1 MYEF2 MYOZ1 NATD1 OTX1 PFKFB1 PKP2 PLA2G15 PPP1R32 PRPF18 PRPF31 PSMB1 RHOA RIN1 SAXO1 SETD5 SH2D4A SHISA6 SIX1 SMCP SMG9 TBC1D22B TBX18 TEKT3 TENT5D TFAP2D TFG TRIM55 TRIM63 TSSK3 TTC23 USP2 VPS37C ZCCHC14 ZNF148 ZNF319 ZNF648 29 interacting genes: APP ATP13A1 CALCOCO2 CCNE1 CHPF COG6 EFHC2 EPM2AIP1 FKBP8 HSF2BP HSPBAP1 LMO2 LRATD1 MB21D2 MID2 NR4A1 PICK1 PLCG1 PLEKHG4 POLR1C RHOA SEPHS2 SLAIN1 SLU7 TBC1D13 TCF4 TRIM27 TRIM54 ZRANB1
Entrez ID 25894 7984
HPRD ID 10890 02932
Ensembl ID ENSG00000196155 ENSG00000050327
Uniprot IDs A0A024R6X4 Q58EX7 Q12774
PDB IDs
Enriched GO Terms of Interacting Partners?
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