A1CF and TNPO2

Number of citations of the paper that reports this interaction (PubMedID 12896982)
25

Data Source:
BioGRID (pull down)
HPRD (in vivo, in vitro)

		A1CF	TNPO2
Description		APOBEC1 complementation factor	transportin 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Apolipoprotein B MRNA Editing Enzyme Complex	Nucleus Cytoplasm
	Molecular Function	RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding MRNA Binding Protein Binding	Protein Binding Nuclear Localization Sequence Binding Small GTPase Binding Nuclear Import Signal Receptor Activity
	Biological Process	MRNA Processing Embryo Implantation MRNA Localization Resulting In Posttranscriptional Regulation Of Gene Expression Cytidine To Uridine Editing MRNA Modification Protein Stabilization	Protein Import Into Nucleus
Pathways		mRNA Editing: C to U Conversion Formation of the Editosome
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Colorectal cancer or advanced adenoma ( 30510241) Estimated glomerular filtration rate ( 31152163 31015462 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Gamma glutamyl transferase levels ( 33339817) Glomerular filtration rate (creatinine) ( 28452372) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Interferon alpha levels in systemic lupus erythematosus ( 25338677) LDL cholesterol ( 30275531) Low density lipoprotein cholesterol levels ( 32154731) Narcolepsy with cataplexy ( 25986216) Serum uric acid levels ( 30993211) Total cholesterol levels ( 30275531) Triglyceride levels ( 32154731) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglycerides ( 30275531) Urate levels ( 31985003 31578528 23263486) Urate levels in lean individuals ( 25811787)	Diffuse large B-cell lymphoma or multiple sclerosis ( 31407831)
Interacting Genes		26 interacting genes: APOBEC1 C19orf54 C9orf24 CAVIN2 CELF2 CYSRT1 DOK3 ECM1 EIF4G1 FHL2 FHL3 HSPB2 HSPB2-C11orf52 KHSRP KLHDC7B KRT31 KRT34 METTL27 OIP5 PLEKHG4 POGZ REL RIMBP3C SYNCRIP TNPO2 TRAF1	53 interacting genes: A1CF APIP BEND7 BIRC7 BIRC8 BLMH C12orf40 C1orf94 CAMK2B CAMK2D CAMK2G CCDC158 CRYAB CTAG1A CTAG1B ELAVL1 EXOC5 FH FTO FUCA2 GCH1 GSC2 KLHL2 KLHL20 KLHL3 KRT75 KRTAP8-1 NME1 NUP98 NXF1 OTX2 PACSIN3 PDLIM7 PIK3CD PINX1 PNMA5 POU6F2 PRMT8 PYCR1 RAN RBM45 RPL4 RPRD1B SERTAD3 SF1 TBX2 TCL1B TERF1 THAP6 TRIM8 TRMT1 ZBTB32 ZC2HC1C
Entrez ID		29974	30000
HPRD ID		10627	04301
Ensembl ID		ENSG00000148584	ENSG00000105576
Uniprot IDs		A0A024QZI9 A0A024QZJ5 A0A024QZM7 B4E1E3 F8W9F8 Q9NQ94	A0A024R7F7 O14787 Q05D48 Q4LE60
PDB IDs		2CPD
Enriched GO Terms of Interacting Partners?
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