FFAR3 and UNC93B1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FFAR3	UNC93B1
Description		free fatty acid receptor 3	unc-93 homolog B1, TLR signaling regulator
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Golgi Membrane Lysosome Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Early Phagosome
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Lipid Binding	Protein Binding Toll-like Receptor Binding
	Biological Process	Mucosal Immune Response Positive Regulation Of Cytokine Production Involved In Immune Response Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Regulation Of Norepinephrine Secretion Positive Regulation Of Chemokine Production Negative Regulation Of Blood Pressure Regulation Of Insulin Receptor Signaling Pathway Regulation Of Hormone Biosynthetic Process Cellular Response To Fatty Acid Regulation Of Peptide Hormone Secretion	Adaptive Immune Response Intracellular Protein Transport Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 7 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Innate Immune Response Defense Response To Virus
Pathways		G alpha (q) signalling events Free fatty acid receptors	Trafficking and processing of endosomal TLR UNC93B1 deficiency - HSE
Drugs
Diseases
GWAS			Schizophrenia x sex interaction ( 34099189) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		13 interacting genes: CD79A COMT CTXN3 EFNA5 LAT LTC4S SERINC1 SLC41A1 TEX264 TOMM6 TREX1 UNC93B1 YIPF1	27 interacting genes: BEST2 CCDC107 CD79A CLDN7 CLPTM1 CREB3L1 EBP ERGIC3 FATE1 FFAR3 GPR101 GPR37L1 GPRC5D HHLA2 KLRC1 LDLRAD1 LEUTX LIME1 MBOAT7 MFF REEP1 SLC16A2 SLC35C2 SSMEM1 SYNDIG1 TM4SF18 TMEM237
Entrez ID		2865	81622
HPRD ID		04823	12191
Ensembl ID		ENSG00000185897	ENSG00000110057
Uniprot IDs		A0A0K0PUW7 O14843	Q9H1C4
PDB IDs			7C76 7CYN
Enriched GO Terms of Interacting Partners?
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