UNC93B1 and MBOAT7

Number of citations of the paper that reports this interaction (PubMedID 21903422)
143

Data Source:
BioGRID (pull down)

		UNC93B1	MBOAT7
Description		unc-93 homolog B1, TLR signaling regulator	membrane bound O-acyltransferase domain containing 7
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosome Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Early Phagosome	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Mitochondria-associated Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Toll-like Receptor Binding	1-acylglycerol-3-phosphate O-acyltransferase Activity Protein Binding O-acyltransferase Activity Acyltransferase Activity 2-acylglycerol-3-phosphate O-acyltransferase Activity Lysophospholipid Acyltransferase Activity
	Biological Process	Adaptive Immune Response Intracellular Protein Transport Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 7 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Innate Immune Response Defense Response To Virus	Phosphatidylinositol Biosynthetic Process Ventricular System Development Layer Formation In Cerebral Cortex Lipid Modification Phosphatidylinositol Acyl-chain Remodeling Phosphatidylcholine Acyl-chain Remodeling Regulation Of Triglyceride Metabolic Process
Pathways		Trafficking and processing of endosomal TLR UNC93B1 deficiency - HSE	Acyl chain remodelling of PI
Drugs
Diseases
GWAS		Schizophrenia x sex interaction ( 34099189) Waist circumference adjusted for body mass index ( 34021172)	Apolipoprotein A1 levels ( 33730874) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Cirrhosis (alcohol related) ( 26482880 32853455) Liver enzyme levels (alkaline phosphatase) ( 33972514) Obesity-related traits ( 23251661) Phosphatidylinositol levels ( 31551469) Serum alkaline phosphatase levels ( 33547301) Serum metabolite levels ( 33031748)
Interacting Genes		27 interacting genes: BEST2 CCDC107 CD79A CLDN7 CLPTM1 CREB3L1 EBP ERGIC3 FATE1 FFAR3 GPR101 GPR37L1 GPRC5D HHLA2 KLRC1 LDLRAD1 LEUTX LIME1 MBOAT7 MFF REEP1 SLC16A2 SLC35C2 SSMEM1 SYNDIG1 TM4SF18 TMEM237	7 interacting genes: ADRA1A BDKRB1 MAPK6 SHANK3 STING1 UBC UNC93B1
Entrez ID		81622	79143
HPRD ID		12191	06925
Ensembl ID		ENSG00000110057	ENSG00000125505
Uniprot IDs		Q9H1C4	Q96N66
PDB IDs		7C76 7CYN
Enriched GO Terms of Interacting Partners?
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