FFAR3 and LTC4S

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FFAR3	LTC4S
Description		free fatty acid receptor 3	leukotriene C4 synthase
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Nuclear Envelope Nuclear Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Nuclear Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Lipid Binding	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Glutathione Peroxidase Activity Protein Binding Enzyme Activator Activity Lipid Binding Identical Protein Binding
	Biological Process	Mucosal Immune Response Positive Regulation Of Cytokine Production Involved In Immune Response Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Regulation Of Norepinephrine Secretion Positive Regulation Of Chemokine Production Negative Regulation Of Blood Pressure Regulation Of Insulin Receptor Signaling Pathway Regulation Of Hormone Biosynthetic Process Cellular Response To Fatty Acid Regulation Of Peptide Hormone Secretion	Leukotriene Metabolic Process Leukotriene Biosynthetic Process Long-chain Fatty Acid Biosynthetic Process Regulation Of Catalytic Activity Cellular Oxidant Detoxification
Pathways		G alpha (q) signalling events Free fatty acid receptors	Synthesis of 5-eicosatetraenoic acids Synthesis of Leukotrienes (LT) and Eoxins (EX) Synthesis of Lipoxins (LX) Biosynthesis of maresin conjugates in tissue regeneration (MCTR) Biosynthesis of protectin and resolvin conjugates in tissue regeneration (PCTR and RCTR)
Drugs			Glutathione Azelastine
Diseases
GWAS
Interacting Genes		13 interacting genes: CD79A COMT CTXN3 EFNA5 LAT LTC4S SERINC1 SLC41A1 TEX264 TOMM6 TREX1 UNC93B1 YIPF1	13 interacting genes: ALOX5 ALOX5AP BACE2 CD79A CREB3L1 EBP FFAR3 FXYD3 GPR152 GPR42 MGST1 SLC7A14 TMEM52B
Entrez ID		2865	4056
HPRD ID		04823	02004
Ensembl ID		ENSG00000185897	ENSG00000213316
Uniprot IDs		A0A0K0PUW7 O14843	Q16873
PDB IDs			2PNO 2UUH 2UUI 3B29 3HKK 3LEO 3PCV 4BPM 4J7T 4J7Y 4JC7 4JCZ 4JRZ 4WAB 5HV9 6R7D
Enriched GO Terms of Interacting Partners?
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