UNC93B1 and GPR37L1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		UNC93B1	GPR37L1
Description		unc-93 homolog B1, TLR signaling regulator	G protein-coupled receptor 37 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosome Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Early Phagosome	Plasma Membrane Integral Component Of Membrane Receptor Complex Ciliary Membrane
	Molecular Function	Protein Binding Toll-like Receptor Binding	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Prosaposin Receptor Activity Peptide Binding
	Biological Process	Adaptive Immune Response Intracellular Protein Transport Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 7 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Innate Immune Response Defense Response To Virus	Negative Regulation Of Systemic Arterial Blood Pressure Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cerebellar Granule Cell Precursor Proliferation Positive Regulation Of MAPK Cascade Negative Regulation Of Neuron Differentiation Negative Regulation Of Smoothened Signaling Pathway Negative Regulation Of Astrocyte Differentiation Negative Regulation Of Hydrogen Peroxide-induced Cell Death
Pathways		Trafficking and processing of endosomal TLR UNC93B1 deficiency - HSE	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases
GWAS		Schizophrenia x sex interaction ( 34099189) Waist circumference adjusted for body mass index ( 34021172)	Age at first sexual intercourse ( 27089180) Diverticular disease ( 30177863)
Interacting Genes		27 interacting genes: BEST2 CCDC107 CD79A CLDN7 CLPTM1 CREB3L1 EBP ERGIC3 FATE1 FFAR3 GPR101 GPR37L1 GPRC5D HHLA2 KLRC1 LDLRAD1 LEUTX LIME1 MBOAT7 MFF REEP1 SLC16A2 SLC35C2 SSMEM1 SYNDIG1 TM4SF18 TMEM237	52 interacting genes: ADGRB3 AQP1 AQP10 ARL13B CD46 CISD2 CLDN7 CLDND2 CLEC2A CREB3L1 CYB561A3 ELOVL4 ERG28 FAM209A FFAR2 FXYD3 FXYD6-FXYD2 GPR152 GPR42 GPX8 IGFBP5 INSIG2 JAGN1 LHFPL5 PDCD1LG2 PLN PRH1 RNF122 RPRM SCARB2 SCARF1 SEC22A SERP1 SLC30A8 STOM SYNPR THAP4 THSD7B TM4SF4 TMEM147 TMEM243 TMEM248 TMEM52B TMEM54 TMEM80 TMEM86A TMEM86B TMEM97 TNFRSF10C TSPAN12 UNC93B1 UPK1B
Entrez ID		81622	9283
HPRD ID		12191	13603
Ensembl ID		ENSG00000110057	ENSG00000170075
Uniprot IDs		Q9H1C4	O60883
PDB IDs		7C76 7CYN
Enriched GO Terms of Interacting Partners?
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