UNC93B1 and SYNDIG1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		UNC93B1	SYNDIG1
Description		unc-93 homolog B1, TLR signaling regulator	synapse differentiation inducing 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosome Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Early Phagosome	Integral Component Of Plasma Membrane Postsynaptic Density Membrane Synaptic Vesicle Membrane Early Endosome Membrane Dendritic Spine Dendritic Shaft Intracellular Membrane-bounded Organelle Cell Body Excitatory Synapse Postsynaptic Density Membrane
	Molecular Function	Protein Binding Toll-like Receptor Binding	Protein Binding Glutamate Receptor Binding Protein Homodimerization Activity
	Biological Process	Adaptive Immune Response Intracellular Protein Transport Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 7 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Innate Immune Response Defense Response To Virus	Intracellular Protein Transport Positive Regulation Of Synapse Assembly Synaptic Vesicle Clustering
Pathways		Trafficking and processing of endosomal TLR UNC93B1 deficiency - HSE
Drugs
Diseases
GWAS		Schizophrenia x sex interaction ( 34099189) Waist circumference adjusted for body mass index ( 34021172)	LDL cholesterol levels in HIV infection ( 33109212) Sucrose liking ( 31005972)
Interacting Genes		27 interacting genes: BEST2 CCDC107 CD79A CLDN7 CLPTM1 CREB3L1 EBP ERGIC3 FATE1 FFAR3 GPR101 GPR37L1 GPRC5D HHLA2 KLRC1 LDLRAD1 LEUTX LIME1 MBOAT7 MFF REEP1 SLC16A2 SLC35C2 SSMEM1 SYNDIG1 TM4SF18 TMEM237	16 interacting genes: AQP6 ELOVL4 FATE1 FFAR2 GPR42 GPRC5D LEPROTL1 MAL MFSD6 PFDN1 SLC16A13 SLC35C2 SLC41A1 TLCD4 TMEM43 UNC93B1
Entrez ID		81622	79953
HPRD ID		12191	12766
Ensembl ID		ENSG00000110057	ENSG00000101463
Uniprot IDs		Q9H1C4	Q9H7V2
PDB IDs		7C76 7CYN
Enriched GO Terms of Interacting Partners?
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