DNAJB6 and CAND2

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		DNAJB6	CAND2
Description		DnaJ heat shock protein family (Hsp40) member B6	cullin associated and neddylation dissociated 2 (putative)
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Z Disc Perinuclear Region Of Cytoplasm	Nucleus Cytosol
	Molecular Function	ATPase Activator Activity DNA Binding Protein Binding Heat Shock Protein Binding Protein Folding Chaperone Unfolded Protein Binding Chaperone Binding	Protein Binding TBP-class Protein Binding
	Biological Process	Protein Folding Actin Cytoskeleton Organization Extracellular Matrix Organization Regulation Of Protein Localization Protein Localization To Nucleus Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Intermediate Filament Organization Negative Regulation Of Transcription, DNA-templated Chorio-allantoic Fusion Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Chorion Development Chaperone-mediated Protein Folding Negative Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat	SCF Complex Assembly Protein Ubiquitination Positive Regulation Of Transcription, DNA-templated
Pathways		Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS		Body mass index ( 28552196) Retinal detachment or retinal break ( 31816047) Waist circumference ( 28552196)	Atrial fibrillation ( 30061737 29892015) Creatine kinase levels ( 29403010) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) HOMA-B (corrected for HOMA-IR) ( 30369944) P wave duration ( 28794112) Waist circumference adjusted for body mass index ( 28552196) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		23 interacting genes: ANKRD1 APP ASAP1 BRMS1 CAND2 DYSF EPHB4 KRT18 MAP3K1 MLF1 MRTO4 MYBPC1 MYOM1 PGM1 PIK3CA POLR1D PTEN SGCG SKAP2 SUPT6H TTN TUBGCP3 USP8	10 interacting genes: CIDEB CNOT3 DNAJB6 FHL2 GLP1R MRPS25 RBX1 SYP TBP UBE3C
Entrez ID		10049	23066
HPRD ID		07107	19120
Ensembl ID		ENSG00000105993	ENSG00000144712
Uniprot IDs		A0A0J9YX62 O75190	O75155
PDB IDs		6U3R 6U3S 7JSQ
Enriched GO Terms of Interacting Partners?
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