UFL1 and ZNF219

Number of citations of the paper that reports this interaction (PubMedID 32545848)
8

Data Source:
BioGRID (two hybrid)

		UFL1	ZNF219
Description		UFM1 specific ligase 1	zinc finger protein 219
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane Protein-containing Complex Site Of Double-strand Break Neuron Projection	Nucleus Nucleoplasm Integral Component Of Membrane
	Molecular Function	Protein Binding Protein Kinase Binding UFM1 Ligase Activity UFM1 Transferase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Histamine Receptor Activity Protein Binding Metal Ion Binding
	Biological Process	Osteoblast Differentiation DNA Repair Cellular Response To DNA Damage Stimulus Positive Regulation Of Cell Population Proliferation Positive Regulation Of Autophagy Histone Modification Erythrocyte Differentiation Negative Regulation Of Protein Ubiquitination Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Localization Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Negative Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Inflammatory Response Hematopoietic Stem Cell Differentiation Positive Regulation Of Glial Cell Proliferation Reticulophagy Protein Ufmylation Response To L-glutamate Negative Regulation Of IRE1-mediated Unfolded Protein Response Protein K69-linked Ufmylation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Neurotransmitter Levels Regulation Of Transcription, DNA-templated G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Chondrocyte Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Limb Bud Formation
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Headache ( 29397368) Migraine ( 27322543) Migraine without aura ( 27322543) Night sleep phenotypes ( 27126917) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) Triglyceride levels ( 32203549) Walking pace ( 33128006)	Metabolite levels ( 23823483) Resting heart rate ( 27798624)
Interacting Genes		18 interacting genes: AHCY AKAP17A ATP4A CDK5RAP3 ENY2 FGB H2AC4 HINFP IRAK1BP1 IRF3 MT1M PPIL1 PTPRO TIPRL TP53 TSC22D3 UFC1 ZNF219	18 interacting genes: AP1M1 BCL2L1 CDK4 CSNK2A2 CTBP1 FAM214B GRIPAP1 GRM3 LMO1 MAPK3 MAPK8 SH3GL2 SH3KBP1 SUFU TRIM41 TTC32 UBASH3A UFL1
Entrez ID		23376	51222
HPRD ID		11109	05435
Ensembl ID		ENSG00000014123	ENSG00000165804
Uniprot IDs		O94874	Q9P2Y4
PDB IDs
Enriched GO Terms of Interacting Partners?
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