UFL1 and TSC22D3

Number of citations of the paper that reports this interaction (PubMedID 32545848)
8

Data Source:
BioGRID (enzymatic study)

		UFL1	TSC22D3
Description		UFM1 specific ligase 1	TSC22 domain family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane Protein-containing Complex Site Of Double-strand Break Neuron Projection	Nucleus Cytosol
	Molecular Function	Protein Binding Protein Kinase Binding UFM1 Ligase Activity UFM1 Transferase Activity	Protein Binding
	Biological Process	Osteoblast Differentiation DNA Repair Cellular Response To DNA Damage Stimulus Positive Regulation Of Cell Population Proliferation Positive Regulation Of Autophagy Histone Modification Erythrocyte Differentiation Negative Regulation Of Protein Ubiquitination Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Localization Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Negative Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Inflammatory Response Hematopoietic Stem Cell Differentiation Positive Regulation Of Glial Cell Proliferation Reticulophagy Protein Ufmylation Response To L-glutamate Negative Regulation Of IRE1-mediated Unfolded Protein Response Protein K69-linked Ufmylation	Regulation Of Transcription By RNA Polymerase II Response To Osmotic Stress Negative Regulation Of Activation-induced Cell Death Of T Cells
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Stimuli-sensing channels
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Headache ( 29397368) Migraine ( 27322543) Migraine without aura ( 27322543) Night sleep phenotypes ( 27126917) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) Triglyceride levels ( 32203549) Walking pace ( 33128006)
Interacting Genes		18 interacting genes: AHCY AKAP17A ATP4A CDK5RAP3 ENY2 FGB H2AC4 HINFP IRAK1BP1 IRF3 MT1M PPIL1 PTPRO TIPRL TP53 TSC22D3 UFC1 ZNF219	15 interacting genes: BRME1 DCLK2 FOS HPCAL4 JUN MAD1L1 MTA2 NFKB1 NFKB2 PLEKHF2 RAF1 REL RELA SUMO1 UFL1
Entrez ID		23376	1831
HPRD ID		11109	04266
Ensembl ID		ENSG00000014123	ENSG00000157514
Uniprot IDs		O94874	Q5JRJ2 Q99576
PDB IDs
Enriched GO Terms of Interacting Partners?
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