UFL1 and IRAK1BP1

Number of citations of the paper that reports this interaction (PubMedID 32545848)
8

Data Source:
BioGRID (two hybrid)

		UFL1	IRAK1BP1
Description		UFM1 specific ligase 1	interleukin 1 receptor associated kinase 1 binding protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane Protein-containing Complex Site Of Double-strand Break Neuron Projection	Nucleus Cytoplasm
	Molecular Function	Protein Binding Protein Kinase Binding UFM1 Ligase Activity UFM1 Transferase Activity	Protein Binding
	Biological Process	Osteoblast Differentiation DNA Repair Cellular Response To DNA Damage Stimulus Positive Regulation Of Cell Population Proliferation Positive Regulation Of Autophagy Histone Modification Erythrocyte Differentiation Negative Regulation Of Protein Ubiquitination Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Localization Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Negative Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Inflammatory Response Hematopoietic Stem Cell Differentiation Positive Regulation Of Glial Cell Proliferation Reticulophagy Protein Ufmylation Response To L-glutamate Negative Regulation Of IRE1-mediated Unfolded Protein Response Protein K69-linked Ufmylation	Immune Response I-kappaB Kinase/NF-kappaB Signaling
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Headache ( 29397368) Migraine ( 27322543) Migraine without aura ( 27322543) Night sleep phenotypes ( 27126917) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) Triglyceride levels ( 32203549) Walking pace ( 33128006)	Blood pressure measurement (high sodium and potassium intervention) ( 24165912) Blood pressure measurement (high sodium intervention) ( 24165912) Blood pressure measurement (low sodium intervention) ( 24165912) Cadmium levels ( 26025379) Daytime nap ( 33568662) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Late-onset Alzheimer's disease ( 27770636) LDL cholesterol levels x loop diuretics use interaction ( 31806883) Macular thickness ( 30535121) SjÃ¶gren's syndrome ( 24097067)
Interacting Genes		18 interacting genes: AHCY AKAP17A ATP4A CDK5RAP3 ENY2 FGB H2AC4 HINFP IRAK1BP1 IRF3 MT1M PPIL1 PTPRO TIPRL TP53 TSC22D3 UFC1 ZNF219	11 interacting genes: IRAK1 MISP PHF1 PRKAB2 RELA RIPPLY1 SCNM1 TFCP2 UFL1 USP20 ZNF410
Entrez ID		23376	134728
HPRD ID		11109	17157
Ensembl ID		ENSG00000014123	ENSG00000146243
Uniprot IDs		O94874	Q5VVH5
PDB IDs
Enriched GO Terms of Interacting Partners?
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