UFL1 and ATP4A

Number of citations of the paper that reports this interaction (PubMedID 32545848)
8

Data Source:
BioGRID (two hybrid)

		UFL1	ATP4A
Description		UFM1 specific ligase 1	ATPase H+/K+ transporting subunit alpha
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane Protein-containing Complex Site Of Double-strand Break Neuron Projection	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane
	Molecular Function	Protein Binding Protein Kinase Binding UFM1 Ligase Activity UFM1 Transferase Activity	Magnesium Ion Binding P-type Sodium:potassium-exchanging Transporter Activity ATP Binding P-type Potassium:proton Transporter Activity ATP Hydrolysis Activity Potassium Ion Binding
	Biological Process	Osteoblast Differentiation DNA Repair Cellular Response To DNA Damage Stimulus Positive Regulation Of Cell Population Proliferation Positive Regulation Of Autophagy Histone Modification Erythrocyte Differentiation Negative Regulation Of Protein Ubiquitination Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Localization Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Negative Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Inflammatory Response Hematopoietic Stem Cell Differentiation Positive Regulation Of Glial Cell Proliferation Reticulophagy Protein Ufmylation Response To L-glutamate Negative Regulation Of IRE1-mediated Unfolded Protein Response Protein K69-linked Ufmylation	Cellular Sodium Ion Homeostasis Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Cellular Potassium Ion Homeostasis Sodium Ion Export Across Plasma Membrane Proton Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Ion transport by P-type ATPases
Drugs			Pantoprazole Omeprazole Lansoprazole Esomeprazole Rabeprazole Dexlansoprazole
Diseases
GWAS		Diastolic blood pressure ( 27841878) Headache ( 29397368) Migraine ( 27322543) Migraine without aura ( 27322543) Night sleep phenotypes ( 27126917) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) Triglyceride levels ( 32203549) Walking pace ( 33128006)	Platelet count ( 29403010)
Interacting Genes		18 interacting genes: AHCY AKAP17A ATP4A CDK5RAP3 ENY2 FGB H2AC4 HINFP IRAK1BP1 IRF3 MT1M PPIL1 PTPRO TIPRL TP53 TSC22D3 UFC1 ZNF219	2 interacting genes: CLK1 UFL1
Entrez ID		23376	495
HPRD ID		11109	00668
Ensembl ID		ENSG00000014123	ENSG00000105675
Uniprot IDs		O94874	A0A384MR29 P20648 Q658V6
PDB IDs
Enriched GO Terms of Interacting Partners?
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