PTPDC1 and LMTK2

Number of citations of the paper that reports this interaction (PubMedID 28065597)
37

Data Source:
BioGRID (two hybrid)

		PTPDC1	LMTK2
Description		protein tyrosine phosphatase domain containing 1	lemur tyrosine kinase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Early Endosome Golgi Apparatus Cytosol Integral Component Of Plasma Membrane Integral Component Of Membrane Growth Cone Neuronal Cell Body Receptor Complex Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity	Protein Serine/threonine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Phosphatase Inhibitor Activity Protein Binding ATP Binding Myosin VI Binding Protein Serine Kinase Activity
	Biological Process	Peptidyl-tyrosine Dephosphorylation Cilium Assembly	Receptor Recycling Protein Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Axonogenesis Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Endocytic Recycling Transferrin Transport Positive Regulation Of Kinase Activity Negative Regulation Of Catalytic Activity Early Endosome To Late Endosome Transport Protein Autophosphorylation
Pathways
Drugs
Diseases
GWAS		Birth weight ( 31043758) Esophageal adenocarcinoma ( 24121790) Heel bone mineral density ( 30598549) Height ( 20881960) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Parkinson's disease ( 26227905) Type 2 diabetes ( 30054458) Waist-hip ratio ( 25673412) Waist-to-hip ratio adjusted for body mass index ( 25673412)	Gamma glutamyl transferase levels ( 29403010 33339817) Hemoglobin levels ( 32327693) Prostate cancer ( 18264097) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408)
Interacting Genes		8 interacting genes: AATK CRKL ERBB3 ERBB4 LMTK2 MAPK1 MID2 TEX11	24 interacting genes: CDC14A CDC25C CDK5 CDK5R1 DUSP14 DUSP19 DUSP29 DUSP6 ILKAP MTMR6 PPM1A PPM1F PPM1K PPP1CA PPP1CB PPP1CC PPP1R2 PPP3CB PTPDC1 PTPN12 PTPN6 PTPRR STYX TPTE2
Entrez ID		138639	22853
HPRD ID		06689	13994
Ensembl ID		ENSG00000158079	ENSG00000164715
Uniprot IDs		A0A087WTF0 A2A3K4 A8K0X7	Q8IWU2
PDB IDs
Enriched GO Terms of Interacting Partners?
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