LMTK2 and ILKAP

Number of citations of the paper that reports this interaction (PubMedID 28065597)
37

Data Source:
BioGRID (two hybrid)

		LMTK2	ILKAP
Description		lemur tyrosine kinase 2	ILK associated serine/threonine phosphatase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Early Endosome Golgi Apparatus Cytosol Integral Component Of Plasma Membrane Integral Component Of Membrane Growth Cone Neuronal Cell Body Receptor Complex Perinuclear Region Of Cytoplasm Recycling Endosome	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Serine/threonine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Phosphatase Inhibitor Activity Protein Binding ATP Binding Myosin VI Binding Protein Serine Kinase Activity	Protein Binding Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Receptor Recycling Protein Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Axonogenesis Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Endocytic Recycling Transferrin Transport Positive Regulation Of Kinase Activity Negative Regulation Of Catalytic Activity Early Endosome To Late Endosome Transport Protein Autophosphorylation	Protein Dephosphorylation
Pathways
Drugs
Diseases
GWAS		Gamma glutamyl transferase levels ( 29403010 33339817) Hemoglobin levels ( 32327693) Prostate cancer ( 18264097) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408)	Hemoglobin levels ( 32327693) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Phospholipid levels (plasma) ( 22359512) Red cell distribution width ( 27863252)
Interacting Genes		24 interacting genes: CDC14A CDC25C CDK5 CDK5R1 DUSP14 DUSP19 DUSP29 DUSP6 ILKAP MTMR6 PPM1A PPM1F PPM1K PPP1CA PPP1CB PPP1CC PPP1R2 PPP3CB PTPDC1 PTPN12 PTPN6 PTPRR STYX TPTE2	23 interacting genes: AATK CHEK1 EGFR EPHA2 EPHA3 ERBB2 ERBB3 ERBB4 FBXO7 HGS IGF1R ILK KDR KIT LMTK2 MAPK14 MUSK OGT PTK7 ROR1 ROR2 RPS6KA3 TEK
Entrez ID		22853	80895
HPRD ID		13994	17147
Ensembl ID		ENSG00000164715	ENSG00000132323
Uniprot IDs		Q8IWU2	Q9H0C8
PDB IDs
Enriched GO Terms of Interacting Partners?
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