LMTK2 and DUSP29

Number of citations of the paper that reports this interaction (PubMedID 28065597)
37

Data Source:
BioGRID (two hybrid)

		LMTK2	DUSP29
Description		lemur tyrosine kinase 2	dual specificity phosphatase 29
Image		No pdb structure
GO Annotations	Cellular Component	Early Endosome Golgi Apparatus Cytosol Integral Component Of Plasma Membrane Integral Component Of Membrane Growth Cone Neuronal Cell Body Receptor Complex Perinuclear Region Of Cytoplasm Recycling Endosome	Nucleus Cytoplasm Protein-containing Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Phosphatase Inhibitor Activity Protein Binding ATP Binding Myosin VI Binding Protein Serine Kinase Activity	Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity MAP Kinase Phosphatase Activity Protein Homodimerization Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Receptor Recycling Protein Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Axonogenesis Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Endocytic Recycling Transferrin Transport Positive Regulation Of Kinase Activity Negative Regulation Of Catalytic Activity Early Endosome To Late Endosome Transport Protein Autophosphorylation	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation Glucose Homeostasis Muscle Cell Differentiation Negative Regulation Of MAPK Cascade Negative Regulation Of ERK1 And ERK2 Cascade
Pathways
Drugs
Diseases
GWAS		Gamma glutamyl transferase levels ( 29403010 33339817) Hemoglobin levels ( 32327693) Prostate cancer ( 18264097) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408)
Interacting Genes		24 interacting genes: CDC14A CDC25C CDK5 CDK5R1 DUSP14 DUSP19 DUSP29 DUSP6 ILKAP MTMR6 PPM1A PPM1F PPM1K PPP1CA PPP1CB PPP1CC PPP1R2 PPP3CB PTPDC1 PTPN12 PTPN6 PTPRR STYX TPTE2	25 interacting genes: AATK ARPC3 ASPA C17orf75 CNTROB DDIT4L EPHA2 ERBB3 GOLGA6A IGF1R LMTK2 LNX1 NIF3L1 NOC4L PICK1 POLR2G PSMB5 PTK7 RNF40 ROR1 ROR2 SRSF11 STX11 TCF4 TEPSIN
Entrez ID		22853	338599
HPRD ID		13994	16846
Ensembl ID		ENSG00000164715	ENSG00000188716
Uniprot IDs		Q8IWU2	Q68J44
PDB IDs			2Y96
Enriched GO Terms of Interacting Partners?
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